Total skin electron treatment of extensive cutaneous lesions in Kaposi sarcoma
We report on a 62-year-old HIV-negative male patient with Kaposi sarcoma. After 8 years of treatment of smaller localized skin lesions with surgery and local radiotherapy, the patient developed extensive lesions of the whole skin. The extent of the lesions required the administration of the total sk...
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Veröffentlicht in: | Croatian medical journal 2002-06, Vol.43 (3), p.342-345 |
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creator | Margaretić, Damir Faj, Dario Tomas, Ilijan Dmitrović, Branko Krajina, Zdenko |
description | We report on a 62-year-old HIV-negative male patient with Kaposi sarcoma. After 8 years of treatment of smaller localized skin lesions with surgery and local radiotherapy, the patient developed extensive lesions of the whole skin. The extent of the lesions required the administration of the total skin electron therapy (TSET). Until then, TSET had been used at our Department only for the treatment of mycosis fungoides. The dose delivered was 30 Gy higher than in a conventional radiotherapy treatment, where doses are usually between 8 and 24 Gy. Six months after the TSET therapy, the lesions completely regressed, except for two large facial lesions, which were surgically removed. Major side effects were mild erythema and hyperpigmentation of the skin. Erythema disappeared a month after the therapy. |
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After 8 years of treatment of smaller localized skin lesions with surgery and local radiotherapy, the patient developed extensive lesions of the whole skin. The extent of the lesions required the administration of the total skin electron therapy (TSET). Until then, TSET had been used at our Department only for the treatment of mycosis fungoides. The dose delivered was 30 Gy higher than in a conventional radiotherapy treatment, where doses are usually between 8 and 24 Gy. Six months after the TSET therapy, the lesions completely regressed, except for two large facial lesions, which were surgically removed. Major side effects were mild erythema and hyperpigmentation of the skin. Erythema disappeared a month after the therapy.</description><identifier>ISSN: 0353-9504</identifier><identifier>PMID: 12035143</identifier><language>eng</language><publisher>Croatia</publisher><subject>Biopsy, Needle ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Radiotherapy Dosage ; Radiotherapy, High-Energy - methods ; Sarcoma, Kaposi - pathology ; Sarcoma, Kaposi - radiotherapy ; Severity of Illness Index ; Skin Neoplasms - pathology ; Skin Neoplasms - radiotherapy ; Treatment Outcome ; Whole-Body Irradiation - methods</subject><ispartof>Croatian medical journal, 2002-06, Vol.43 (3), p.342-345</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12035143$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Margaretić, Damir</creatorcontrib><creatorcontrib>Faj, Dario</creatorcontrib><creatorcontrib>Tomas, Ilijan</creatorcontrib><creatorcontrib>Dmitrović, Branko</creatorcontrib><creatorcontrib>Krajina, Zdenko</creatorcontrib><title>Total skin electron treatment of extensive cutaneous lesions in Kaposi sarcoma</title><title>Croatian medical journal</title><addtitle>Croat Med J</addtitle><description>We report on a 62-year-old HIV-negative male patient with Kaposi sarcoma. After 8 years of treatment of smaller localized skin lesions with surgery and local radiotherapy, the patient developed extensive lesions of the whole skin. The extent of the lesions required the administration of the total skin electron therapy (TSET). Until then, TSET had been used at our Department only for the treatment of mycosis fungoides. The dose delivered was 30 Gy higher than in a conventional radiotherapy treatment, where doses are usually between 8 and 24 Gy. Six months after the TSET therapy, the lesions completely regressed, except for two large facial lesions, which were surgically removed. Major side effects were mild erythema and hyperpigmentation of the skin. Erythema disappeared a month after the therapy.</description><subject>Biopsy, Needle</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy, High-Energy - methods</subject><subject>Sarcoma, Kaposi - pathology</subject><subject>Sarcoma, Kaposi - radiotherapy</subject><subject>Severity of Illness Index</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - radiotherapy</subject><subject>Treatment Outcome</subject><subject>Whole-Body Irradiation - methods</subject><issn>0353-9504</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1PwzAYhD2AaCn8BeSJLZK_4tgjqvgSFSxljlzntWRw7GA7CP49kVqmG-650-nO0Jrwlje6JWKFLkv5IIQRIeQFWlG2WFTwNXrdp2oCLp8-Yghga04R1wymjhArTg7DT4VY_DdgO1cTIc0FByg-xYKX0IuZUvG4mGzTaK7QuTOhwPVJN-j94X6_fWp2b4_P27tdMzHS1QasYc4RLh3nQFuhKDnAYJU2WgETjggOgyaqdcpJ5UAzoKIDxmTLpOSSb9DtsXfK6WuGUvvRFwshHAf2He24ZlIt4M0JnA8jDP2U_Wjyb___AP8DdLxW-Q</recordid><startdate>20020601</startdate><enddate>20020601</enddate><creator>Margaretić, Damir</creator><creator>Faj, Dario</creator><creator>Tomas, Ilijan</creator><creator>Dmitrović, Branko</creator><creator>Krajina, Zdenko</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20020601</creationdate><title>Total skin electron treatment of extensive cutaneous lesions in Kaposi sarcoma</title><author>Margaretić, Damir ; Faj, Dario ; Tomas, Ilijan ; Dmitrović, Branko ; Krajina, Zdenko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p207t-eca2ff036f33e154810bedc89a98e24f043ed9085f8f68fe92e147e2265266363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biopsy, Needle</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy, High-Energy - methods</topic><topic>Sarcoma, Kaposi - pathology</topic><topic>Sarcoma, Kaposi - radiotherapy</topic><topic>Severity of Illness Index</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - radiotherapy</topic><topic>Treatment Outcome</topic><topic>Whole-Body Irradiation - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Margaretić, Damir</creatorcontrib><creatorcontrib>Faj, Dario</creatorcontrib><creatorcontrib>Tomas, Ilijan</creatorcontrib><creatorcontrib>Dmitrović, Branko</creatorcontrib><creatorcontrib>Krajina, Zdenko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Croatian medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Margaretić, Damir</au><au>Faj, Dario</au><au>Tomas, Ilijan</au><au>Dmitrović, Branko</au><au>Krajina, Zdenko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Total skin electron treatment of extensive cutaneous lesions in Kaposi sarcoma</atitle><jtitle>Croatian medical journal</jtitle><addtitle>Croat Med J</addtitle><date>2002-06-01</date><risdate>2002</risdate><volume>43</volume><issue>3</issue><spage>342</spage><epage>345</epage><pages>342-345</pages><issn>0353-9504</issn><abstract>We report on a 62-year-old HIV-negative male patient with Kaposi sarcoma. After 8 years of treatment of smaller localized skin lesions with surgery and local radiotherapy, the patient developed extensive lesions of the whole skin. The extent of the lesions required the administration of the total skin electron therapy (TSET). Until then, TSET had been used at our Department only for the treatment of mycosis fungoides. The dose delivered was 30 Gy higher than in a conventional radiotherapy treatment, where doses are usually between 8 and 24 Gy. Six months after the TSET therapy, the lesions completely regressed, except for two large facial lesions, which were surgically removed. Major side effects were mild erythema and hyperpigmentation of the skin. Erythema disappeared a month after the therapy.</abstract><cop>Croatia</cop><pmid>12035143</pmid><tpages>4</tpages></addata></record> |
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subjects | Biopsy, Needle Follow-Up Studies Humans Male Middle Aged Radiotherapy Dosage Radiotherapy, High-Energy - methods Sarcoma, Kaposi - pathology Sarcoma, Kaposi - radiotherapy Severity of Illness Index Skin Neoplasms - pathology Skin Neoplasms - radiotherapy Treatment Outcome Whole-Body Irradiation - methods |
title | Total skin electron treatment of extensive cutaneous lesions in Kaposi sarcoma |
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