18F-labelled annexin V: a PET tracer for apoptosis imaging

Annexin V can be used to detect apoptotic cells in vitro and in vivo, based on its ability to identify extracellular phosphatidylserine, which arises during apoptosis. In the present study, we examined the synthesis of fluorine-18 labelled annexin V as a positron emission tomography tracer for apopt...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2004-04, Vol.31 (4), p.469-474
Hauptverfasser:	Murakami, Yoshihiro, Takamatsu, Hiroyuki, Taki, Junichi, Tatsumi, Mitsuyoshi, Noda, Akihiro, Ichise, Rikiya, Tait, Jonathan F, Nishimura, Shintaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annexin A5 - pharmacokinetics Apoptosis Fluorine Radioisotopes - pharmacokinetics Male Metabolic Clearance Rate Myocardial Ischemia - diagnostic imaging Myocardial Ischemia - metabolism Organ Specificity Positron-Emission Tomography - methods Radiopharmaceuticals - pharmacokinetics Rats Rats, Wistar Tissue Distribution
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