Antibodies to GAD65 Epitopes at Diagnosis and Over the First 10 years of Clinical Type 1 Diabetes Mellitus

Antibodies to glutamate decarboxylase (GAD65Ab) may persist, and their titres even increase after the clinical onset of type 1 diabetes. To characterize this phenomenon in detail, we analysed sequentially antibodies to GAD65 epitope clusters in a radio‐binding assay in patients with type 1 diabetes....

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Veröffentlicht in:	Scandinavian journal of immunology 2004-03, Vol.59 (3), p.334-340
Hauptverfasser:	Ronkainen, M. S., Savola, K., Knip, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies - immunology C-Reactive Protein - metabolism Child Child, Preschool Diabetes Mellitus, Type 1 - enzymology Diabetes Mellitus, Type 1 - immunology Female Glutamate Decarboxylase - immunology Glycated Hemoglobin A - metabolism HLA-DR Antigens - immunology Humans Immunodominant Epitopes - immunology Infant Insulin - administration & dosage Isoenzymes - immunology Longitudinal Studies Male
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