Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD

Plasma homocysteine and cysteine levels were measured in 90 patients with PD with the MTHFR C677T (T/T) genotype. The authors found that the levels of homocysteine-a possible risk factor for vascular disease-were elevated by 60% in levodopa-treated patients with PD, with the most marked elevation oc...

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Veröffentlicht in:	Neurology 2000-08, Vol.55 (3), p.437-440
Hauptverfasser:	YASUI, K, KOWA, H, NAKASO, K, TAKESHIMA, T, NAKASHIMA, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antiparkinson Agents - administration & dosage Biological and medical sciences Cysteine - blood Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Folic Acid - blood Genotype Homocysteine - blood Humans Levodopa - administration & dosage Male Medical sciences Methylenetetrahydrofolate Reductase (NADPH2) Middle Aged Neurology Oxidoreductases Acting on CH-NH Group Donors - genetics Parkinson Disease - blood Parkinson Disease - drug therapy Parkinson Disease - genetics Point Mutation
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