Determination of 1-Deoxynojirimycin in Mulberry Leaves Using Hydrophilic Interaction Chromatography with Evaporative Light Scattering Detection
A simple and rapid method for determining 1-deoxynojirimycin (DNJ), a potent glucosidase inihibitor present in mulberry leaves (Morus alba and Morus bombysis), by high-performance liquid chromatography coupled to an evaporative light scattering detector (ELSD) has been developed. DNJ was separated f...
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| Veröffentlicht in: | Journal of agricultural and food chemistry 2004-03, Vol.52 (6), p.1415-1418 |
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| container_title | Journal of agricultural and food chemistry |
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| creator | Kimura, Toshiyuki Nakagawa, Kiyotaka Saito, Yuko Yamagishi, Kenji Suzuki, Masahiro Yamaki, Kohji Shinmoto, Hiroshi Miyazawa, Teruo |
| description | A simple and rapid method for determining 1-deoxynojirimycin (DNJ), a potent glucosidase inihibitor present in mulberry leaves (Morus alba and Morus bombysis), by high-performance liquid chromatography coupled to an evaporative light scattering detector (ELSD) has been developed. DNJ was separated from an extract of mulberry leaves on a TSKgel Amide-80 column, which is a representative column for hydrophilic interaction chromatography. During postcolumn detection, DNJ was detected by ELSD and concurrently identified by mass spectrometry. The detection limit was 100 ng. This method is sufficiently sensitive for determining DNJ in mulberry leaves and other related products. Keywords: 1-Deoxynojirimycin; evaporative light scattering detector; mulberry leaves; Morus alba |
| doi_str_mv | 10.1021/jf0306901 |
| format | Article |
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DNJ was separated from an extract of mulberry leaves on a TSKgel Amide-80 column, which is a representative column for hydrophilic interaction chromatography. During postcolumn detection, DNJ was detected by ELSD and concurrently identified by mass spectrometry. The detection limit was 100 ng. This method is sufficiently sensitive for determining DNJ in mulberry leaves and other related products. 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Agric. Food Chem</addtitle><description>A simple and rapid method for determining 1-deoxynojirimycin (DNJ), a potent glucosidase inihibitor present in mulberry leaves (Morus alba and Morus bombysis), by high-performance liquid chromatography coupled to an evaporative light scattering detector (ELSD) has been developed. DNJ was separated from an extract of mulberry leaves on a TSKgel Amide-80 column, which is a representative column for hydrophilic interaction chromatography. During postcolumn detection, DNJ was detected by ELSD and concurrently identified by mass spectrometry. The detection limit was 100 ng. This method is sufficiently sensitive for determining DNJ in mulberry leaves and other related products. Keywords: 1-Deoxynojirimycin; evaporative light scattering detector; mulberry leaves; Morus alba</description><subject>1-Deoxynojirimycin - analysis</subject><subject>Biological and medical sciences</subject><subject>Chromatography, High Pressure Liquid - methods</subject><subject>Food industries</subject><subject>Fruit and vegetable industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Light</subject><subject>Methods of analysis, processing and quality control, regulation, standards</subject><subject>Morus - chemistry</subject><subject>Plant Leaves - chemistry</subject><subject>Scattering, Radiation</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEFv0zAYhi0EYmVw4A8gX0DiEPCXNLZ7ZN3Yhsqo2HbhYjnul8YliYOdlOVX8Jdx12rjgGTJh-95H39-CXkN7AOwFD5uSpYxPmPwhEwgT1mSA8inZMLiMJE5hyPyIoQNY0zmgj0nR5DHAEg5IX9OsUff2Fb31rXUlRSSU3R3Y-s21ttmNLal8Xwd6gK9H-kC9RYDvQ22XdOLceVdV9naGnrZRpE295p55V2je7f2uqtG-tv2FT3b6s75-MwW6cKuq55eG93HzE602-I--pI8K3Ud8NXhPia3n89u5hfJ4tv55fzTItGZmPWJmBaFybHkwJiRophpLHJWrADKqUQpp7ycQaoNphJ0AWbKM8NXMgVZxG8LzI7Ju7238-7XgKFXjQ0G61q36IagBIiMM84j-H4PGu9C8FiqLtai_aiAqV376qH9yL45SIeiwdUjeag7Am8PgA5G16XXrbHhH46nKRNZ5JI9Z0OPdw9z7X8qLjKRq5vltfp-tfzx5fzqRC0fvdoEtXGDb2N3_1nwL3N9qnk</recordid><startdate>20040324</startdate><enddate>20040324</enddate><creator>Kimura, Toshiyuki</creator><creator>Nakagawa, Kiyotaka</creator><creator>Saito, Yuko</creator><creator>Yamagishi, Kenji</creator><creator>Suzuki, Masahiro</creator><creator>Yamaki, Kohji</creator><creator>Shinmoto, Hiroshi</creator><creator>Miyazawa, Teruo</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040324</creationdate><title>Determination of 1-Deoxynojirimycin in Mulberry Leaves Using Hydrophilic Interaction Chromatography with Evaporative Light Scattering Detection</title><author>Kimura, Toshiyuki ; Nakagawa, Kiyotaka ; Saito, Yuko ; Yamagishi, Kenji ; Suzuki, Masahiro ; Yamaki, Kohji ; Shinmoto, Hiroshi ; Miyazawa, Teruo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a379t-74bbc5ef6100c87b9aeb50bd11f48e8846f912ace281ab1c463c6d8218b1887e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>1-Deoxynojirimycin - analysis</topic><topic>Biological and medical sciences</topic><topic>Chromatography, High Pressure Liquid - methods</topic><topic>Food industries</topic><topic>Fruit and vegetable industries</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Light</topic><topic>Methods of analysis, processing and quality control, regulation, standards</topic><topic>Morus - chemistry</topic><topic>Plant Leaves - chemistry</topic><topic>Scattering, Radiation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kimura, Toshiyuki</creatorcontrib><creatorcontrib>Nakagawa, Kiyotaka</creatorcontrib><creatorcontrib>Saito, Yuko</creatorcontrib><creatorcontrib>Yamagishi, Kenji</creatorcontrib><creatorcontrib>Suzuki, Masahiro</creatorcontrib><creatorcontrib>Yamaki, Kohji</creatorcontrib><creatorcontrib>Shinmoto, Hiroshi</creatorcontrib><creatorcontrib>Miyazawa, Teruo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kimura, Toshiyuki</au><au>Nakagawa, Kiyotaka</au><au>Saito, Yuko</au><au>Yamagishi, Kenji</au><au>Suzuki, Masahiro</au><au>Yamaki, Kohji</au><au>Shinmoto, Hiroshi</au><au>Miyazawa, Teruo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of 1-Deoxynojirimycin in Mulberry Leaves Using Hydrophilic Interaction Chromatography with Evaporative Light Scattering Detection</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2004-03-24</date><risdate>2004</risdate><volume>52</volume><issue>6</issue><spage>1415</spage><epage>1418</epage><pages>1415-1418</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>A simple and rapid method for determining 1-deoxynojirimycin (DNJ), a potent glucosidase inihibitor present in mulberry leaves (Morus alba and Morus bombysis), by high-performance liquid chromatography coupled to an evaporative light scattering detector (ELSD) has been developed. DNJ was separated from an extract of mulberry leaves on a TSKgel Amide-80 column, which is a representative column for hydrophilic interaction chromatography. During postcolumn detection, DNJ was detected by ELSD and concurrently identified by mass spectrometry. The detection limit was 100 ng. This method is sufficiently sensitive for determining DNJ in mulberry leaves and other related products. Keywords: 1-Deoxynojirimycin; evaporative light scattering detector; mulberry leaves; Morus alba</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>15030188</pmid><doi>10.1021/jf0306901</doi><tpages>4</tpages></addata></record> |
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| subjects | 1-Deoxynojirimycin - analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Food industries Fruit and vegetable industries Fundamental and applied biological sciences. Psychology General aspects Light Methods of analysis, processing and quality control, regulation, standards Morus - chemistry Plant Leaves - chemistry Scattering, Radiation |
| title | Determination of 1-Deoxynojirimycin in Mulberry Leaves Using Hydrophilic Interaction Chromatography with Evaporative Light Scattering Detection |
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