Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats

The rate of liver glucokinase (GK) translocation from the nucleus to the cytoplasm in response to intraduodenal glucose infusion and the effect of physiological rises of plasma glucose and/or insulin on GK translocation were examined in 6-h-fasted conscious rats. Intraduodenal glucose infusion (28 m...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2004-04, Vol.286 (4), p.G627-G634
Hauptverfasser:	Chu, Chang An, Fujimoto, Yuka, Igawa, Kayano, Grimsby, Joseph, Grippo, Joseph F, Magnuson, Mark A, Cherrington, Alan D, Shiota, Masakazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - metabolism Blotting, Western Catheterization, Peripheral Duodenum - physiology Glucokinase - metabolism Glucose - administration & dosage Glucose - pharmacology Immunohistochemistry Insulin - blood Intubation, Gastrointestinal Liver - enzymology Liver Circulation - drug effects Male Microscopy, Confocal Protein Transport Rats Rats, Sprague-Dawley Renal Circulation - drug effects
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