Synonymous Genetic Polymorphisms within Brazilian Human Immunodeficiency Virus Type 1 Subtypes May Influence Mutational Routes to Drug Resistance

Background. Most published data on antiretroviral-drug resistance is generated from in vitro or in vivo studies of subtype B virus. However, this subtype is associated with !10% of HIV infections worldwide, and it is essential to explore subtype-specific determinants of drug resistance. One potentia...

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Veröffentlicht in:	The Journal of infectious diseases 2004-04, Vol.189 (7), p.1232-1238
Hauptverfasser:	Dumans, Ana T., Soares, Marcelo A., Machado, Elizabeth S., Hué, Stéphane, Brindeiro, Rodrigo M., Pillay, Deenan, Tanuri, Amilcar
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Base Sequence Biological and medical sciences Brazil Codon - genetics Codons DNA, Viral - chemistry DNA, Viral - genetics Drug resistance Drug Resistance, Viral - genetics Fundamental and applied biological sciences. Psychology Genetic mutation HIV HIV 1 HIV Infections - drug therapy HIV Protease - genetics HIV-1 - genetics HIV-1 - metabolism HIV/AIDS Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Medical genetics Medical sciences Microbiology Miscellaneous Molecular Sequence Data Nucleotide sequences Point Mutation - genetics Polymorphism, Genetic RNA-Directed DNA Polymerase - genetics Sequence Alignment Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology Viruses
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