Discordance between Expression and Genome Transfer Titering of HSV Amplicon Vectors: Recommendation for Standardized Enumeration

Herpes simplex virus-derived amplicon vectors are well suited to the development of gene-based therapy for neurodegenerative diseases. The plasmid-based amplicon vector system allows for facile introduction of transcription units, possesses the potential for carrying gene inserts up to approximately...

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Veröffentlicht in:	Molecular therapy 2000-03, Vol.1 (3), p.294-299
Hauptverfasser:	Bowers, W.J., Howard, D.F., Federoff, H.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Adenoviruses amplicon Animals Cell Line Cricetinae Dentistry Developmental biology Gene Expression Gene therapy Gene Transfer Techniques - standards Genetic Vectors Genomes herpes simplex virus Herpes viruses Herpesvirus 1, Human - genetics Infections Methods Mice Penicillin Plasmids Polymerase Chain Reaction Promoter Regions, Genetic quantitative PCR titering Vectors (Biology)
Online-Zugang:	Volltext
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