Survival signaling in resting B cells

The survival of mature resting B cells in the periphery depends on signaling from the B-cell receptor (BCR) and the B-cell activating factor of the TNF family receptor (BAFF-R). Engagement of both receptors promotes NF-κB activity, which contributes to B-cell survival through different pathways. BCR...

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Veröffentlicht in:	Current opinion in immunology 2004-04, Vol.16 (2), p.251-255
Hauptverfasser:	Patke, Alina, Mecklenbräuker, Ingrid, Tarakhovsky, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Cell Activation Factor Receptor B-Lymphocytes - metabolism Cell Survival Membrane Proteins - metabolism Mice NF-kappa B - metabolism Receptors, Tumor Necrosis Factor - metabolism Signal Transduction
Online-Zugang:	Volltext
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