Oral valganciclovir in children: single dose pharmacokinetics in a six-year-old girl

We report a pharmacokinetic study in a 6-year-old girl with congenital human immunodeficiency virus type 1 and cytomegalovirus coinfection maintained on iv ganciclovir for 6 years. Increasing infection and thrombosis caused by her iv device necessitated alternative therapy. Single dose pharmacokinet...

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Veröffentlicht in:	The Pediatric infectious disease journal 2004-03, Vol.23 (3), p.263-266
Hauptverfasser:	BURRI, MARCUS, WILTSHIRE, HUGH, KAHLERT, CHRISTIAN, WOUTERS, GEORGE, RUDIN, CHRISTOPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral AIDS-Related Opportunistic Infections - drug therapy Antiviral Agents - pharmacokinetics Antiviral Agents - therapeutic use Area Under Curve Biological and medical sciences Biological Availability Child Chromatography, High Pressure Liquid Cytomegalovirus Infections - drug therapy Female Fundamental and applied biological sciences. Psychology Ganciclovir - analogs & derivatives Ganciclovir - pharmacokinetics Ganciclovir - therapeutic use General aspects Humans Mass Spectrometry Medical sciences Microbiology Valganciclovir
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