Apoptosis Induced by Oxaliplatin in Human Colon Cancer HCT15 Cell Line

Background: Oxaliplatin (L-OHP), active in a wide range of human and animal tumours, also CDDP-resistant, possesses unique molecular characteristics of action. However, the mechanisms by which the damage induced by L-OHP triggers a death signal are not yet fully defined. Materials and Methods: After...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Anticancer research 2004-01, Vol.24 (1), p.219-226
Hauptverfasser:	MARCHETTI, Paolo, GALLA, Domenico A. P, RUSSO, F. Paola, RICEVUTO, Enrico, FLATI, Vincenzo, PORZIO, Giampiero, FICORELLA, Corrado, CIFONE, M. Grazia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - enzymology Adenocarcinoma - pathology Antineoplastic Agents - pharmacology Apoptosis - drug effects Apoptosis - physiology Biological and medical sciences Caspases - metabolism Cell Line, Tumor Colorectal Neoplasms - drug therapy Colorectal Neoplasms - enzymology Colorectal Neoplasms - pathology Cytochromes c - secretion Enzyme Activation - drug effects Fas Ligand Protein fas Receptor - physiology Gastroenterology. Liver. Pancreas. Abdomen Humans Intracellular Membranes - drug effects Intracellular Membranes - physiology Isoenzymes - metabolism Medical sciences Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - physiology Membrane Potentials - drug effects Mitochondria - drug effects Mitochondria - physiology Mitochondria - secretion Organoplatinum Compounds - pharmacology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!