Localization of heparanase in normal and pathological human placenta

Degradation of extracellular matrix (ECM) components is critical for invasion. Heparan sulphate proteoglycans are abundant in the ECM of the placenta and the decidua, hence their degradation may disassemble the matrix and facilitate placentation and trophoblast invasion. This study investigates the...

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Veröffentlicht in:	Molecular human reproduction 2002-06, Vol.8 (6), p.566-573
Hauptverfasser:	Haimov-Kochman, Ronit, Friedmann, Yael, Prus, Diana, Goldman-Wohl, Debra S., Greenfield, Caryn, Anteby, Eyal Y., Aviv, Ayelet, Vlodavsky, Israel, Yagel, Simcha
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Gestational Age Glucuronidase - genetics Glucuronidase - metabolism heparanase Humans hydatidiform mole Hydatidiform Mole - enzymology Hydatidiform Mole - pathology Immunohistochemistry In Situ Hybridization invasion Mother. Fetoplacental unit. Mammary gland. Milk placenta Placenta - cytology Placenta - enzymology Placenta - pathology Pregnancy Pregnancy, Ectopic - pathology Pregnancy. Parturition. Lactation Reverse Transcriptase Polymerase Chain Reaction trophoblast Vertebrates: reproduction
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