Proteomic analysis and molecular characterization of tissue ferritin light chain in hepatocellular carcinoma

To investigate a molecular basis for iron depletion in human hepatocellular carcinoma (HCC), 19 cases of HCC were analyzed by two-dimensional electrophoresis (2DE) and matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). Results were compared with those of paired adjacent nontum...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2002-06, Vol.35 (6), p.1459-1466
Hauptverfasser:	Park, Kang-Sik, Kim, Hoguen, Kim, Nam-Gyun, Cho, Sang Yun, Choi, Kun-Ho, Seong, Je Kyung, Paik, Young-Ki
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Blotting, Western Carcinoma, Hepatocellular - chemistry Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Digestive system Electrophoresis, Gel, Two-Dimensional Ferritins - analysis Ferritins - genetics Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Iron - metabolism Liver - chemistry Liver - metabolism Liver - pathology Liver Neoplasms - chemistry Liver Neoplasms - metabolism Liver Neoplasms - pathology Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prospective Studies Proteome - analysis Reverse Transcriptase Polymerase Chain Reaction Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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