MICRONIZATION ENHANCES THE PROTECTIVE EFFECT OF PURIFIED FLAVONOID FRACTION AGAINST POSTISCHAEMIC MICROVASCULAR INJURY IN THE HAMSTER CHEEK POUCH

SUMMARY 1. The present study was designed to evaluate the effect of micronization on the protective effect of the purified flavonoid fraction (MPFF) on increases in macromolecular permeability induced by ischaemia–reperfusion in the hamster cheek pouch microcirculation. 2. Male hamsters (Mesocricetu...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 2004-03, Vol.31 (3), p.159-162
Hauptverfasser:	Cyrino, Fátima ZGA, Bottino, Daniel A, Lerond, Laurence, Bouskela, Eliete
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Capillary Permeability - drug effects Cheek - blood supply cheek pouch Cricetinae Diosmin - administration & dosage Diosmin - pharmacology Drug Combinations hamster Hesperidin - administration & dosage Hesperidin - pharmacology Ischemia - complications Ischemia - physiopathology macromolecular permeability Male Mesocricetus Microcirculation - drug effects micronization micronized purified flavonoid fraction Particle Size Protective Agents - administration & dosage Protective Agents - pharmacology Regional Blood Flow - drug effects Reperfusion Reperfusion Injury - prevention & control
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