Ischemic preconditioning attenuates ischemia-reperfusion-induced mucosal apoptosis by inhibiting the mitochondria-dependent pathway in rat small intestine

Ischemic preconditioning provides a way of protecting organs from damage inflicted with prolonged ischemia-reperfusion. In this study, we investigated the mechanism of ischemic preconditioning involved in inhibition of prolonged ischemia-reperfusion-induced mucosal apoptosis in rat small intestine....

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2004-04, Vol.286 (4), p.G580-G587
Hauptverfasser:	Wu, Bin, Ootani, Akifumi, Iwakiri, Ryuichi, Fujise, Takehiro, Tsunada, Seiji, Toda, Shuji, Fujimoto, Kazuma
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - physiology Blotting, Western Cytochromes c - metabolism DNA - isolation & purification DNA Fragmentation Electrophoresis, Agar Gel In Situ Nick-End Labeling Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Intestinal Mucosa - physiology Intestine, Small - physiology Ischemic Preconditioning Lipid Peroxidation - physiology Male Membrane Potentials - physiology Mitochondria - physiology Rats Rats, Sprague-Dawley Reactive Oxygen Species - metabolism Reperfusion Injury - pathology Signal Transduction - physiology Sulfhydryl Compounds - metabolism
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