Alpha8beta1 integrin is upregulated in myofibroblasts of fibrotic and scarring myocardium

Integrins mediate cell attachment to the extracellular matrix (ECM) regulating migration, proliferation, and differentiation. We previously reported the presence of alpha8beta1 integrin on cultured cardiac fibroblasts. Extending this information, we localized alpha8beta1 integrin in normal rat myoca...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2004-03, Vol.36 (3), p.343-353
Hauptverfasser:	Bouzeghrane, F, Mercure, C, Reudelhuber, T L, Thibault, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - administration & dosage Animals Blotting, Western Fibrosis Immunohistochemistry Infusion Pumps, Implantable Injections, Subcutaneous Integrins - metabolism Male Myocardium - metabolism Myocardium - pathology Rats Rats, Sprague-Dawley Up-Regulation - drug effects Up-Regulation - physiology Vasoconstrictor Agents - administration & dosage
Online-Zugang:	Volltext
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