Inhibition of FGF signaling causes expansion of the endoderm in Xenopus

Fibroblast growth factor (FGF) is established as an initiator of signaling events critical for neurogenesis and mesoderm formation during early Xenopus embryogenesis. However, less is known about the role FGF signaling plays in endoderm specification. Here, we show for the first time that endoderm-s...

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Veröffentlicht in:	Biochemical and biophysical research communications 2004-02, Vol.315 (1), p.100-106
Hauptverfasser:	Cha, Sang-Wook, Hwang, Yoo-Seok, Chae, Jung-Pil, Lee, Sung-Young, Lee, Hyun-Shik, Daar, Ira, Park, Mae Ja, Kim, Jaebong
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen - embryology Animals Body Patterning - physiology Embryogenesis Endoderm - cytology Endoderm - physiology FGF Fibroblast Growth Factors - antagonists & inhibitors Fibroblast Growth Factors - physiology Gene Expression Regulation, Developmental Mesendoderm specification Mesoderm - physiology Phenotype Pyrroles - pharmacology Receptors, Fibroblast Growth Factor - antagonists & inhibitors Receptors, Fibroblast Growth Factor - metabolism RNA - metabolism Signal Transduction - physiology Xenopus Xenopus laevis
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