Visual cortex excitability increases during visual mental imagery—a TMS study in healthy human subjects
Previous neuroimaging studies provided evidence that visual mental imagery relies, in part, on the primary visual cortex. We hypothesized that, analogous to the finding that motor imagery increases the excitability of motor cortex, visual imagery should increase visual cortex excitability, as indexe...
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| Veröffentlicht in: | Brain research 2002-05, Vol.938 (1), p.92-97 |
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| creator | Sparing, Roland Mottaghy, Felix M. Ganis, Giorgio Thompson, William L. Töpper, Rudolf Kosslyn, Stephen M. Pascual-Leone, Alvaro |
| description | Previous neuroimaging studies provided evidence that visual mental imagery relies, in part, on the primary visual cortex. We hypothesized that, analogous to the finding that motor imagery increases the excitability of motor cortex, visual imagery should increase visual cortex excitability, as indexed by a decrease in the phosphene threshold (PT). In order to test visual cortex excitability, the primary visual cortex was stimulated with transcranial magnetic stimulation (TMS), so as to elicite phosphenes in the right lower visual quadrant. Subjects performed a visual imagery task and an auditory control task. We applied TMS with increasing intensity to determine the PT for each subject. Independent of the quadrant in which subjects placed their visual images, imagery decreased PT compared to baseline PT; in contrast, the auditory task did not change PT. These findings demonstrate for the first time a short-term, task-dependent modulation of PT. These results constitute evidence that early visual areas participate in visual imagery processing. |
| doi_str_mv | 10.1016/S0006-8993(02)02478-2 |
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These results constitute evidence that early visual areas participate in visual imagery processing.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Eye and associated structures. Visual pathways and centers. Vision</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Imagery (Psychotherapy)</subject><subject>Magnetics</subject><subject>Male</subject><subject>Phosphene threshold</subject><subject>Phosphenes</subject><subject>Primary visual cortex</subject><subject>Reference Values</subject><subject>Space life sciences</subject><subject>Transcranial magnetic stimulation</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Visual Cortex - physiology</subject><subject>Visual mental imagery</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1uFDEQhS0EIpPAEUDegMKiwXa7bfcqQhF_UhCLjNha1XZ1xlH_BNsdZXYcghNyEjyZEVlmVbLqe1Xl9wh5xdl7zrj6cMkYU5Vp2_qUiXdMSG0q8YSsuNGiUkKyp2T1Hzkixyldl2ddt-w5OeKC1byRbEXCz5AWGKibY8Y7incuZOjCEPKWhslFhISJ-iWG6Yre7tkRp1xKGOEK4_bv7z9A198vacqL34noBmHImy3dLCNMNC3dNbqcXpBnPQwJXx7qCVl__rQ-_1pd_Pjy7fzjReXKQblSHhgarxX2PUivnddYt9orV_rQOWgcM6LrPHS86Q2vdeMNNkICqNKrT8jb_dibOP9aMGU7huRwGGDCeUlWc81lMelRkBsplZGigM0edHFOKWJvb2L5e9xazuwuC3ufhd0ZbZmw91nYne71YcHSjegfVAfzC_DmAEByMPQRJhfSA1ertmk1L9zZnsNi223AaJMLODn0IRZnrZ_DI6f8A63FqX0</recordid><startdate>20020531</startdate><enddate>20020531</enddate><creator>Sparing, Roland</creator><creator>Mottaghy, Felix M.</creator><creator>Ganis, Giorgio</creator><creator>Thompson, William L.</creator><creator>Töpper, Rudolf</creator><creator>Kosslyn, Stephen M.</creator><creator>Pascual-Leone, Alvaro</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20020531</creationdate><title>Visual cortex excitability increases during visual mental imagery—a TMS study in healthy human subjects</title><author>Sparing, Roland ; Mottaghy, Felix M. ; Ganis, Giorgio ; Thompson, William L. ; Töpper, Rudolf ; Kosslyn, Stephen M. ; Pascual-Leone, Alvaro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-6da0e8d76effa4d7cd7e397d6cc54abca5c082bbdab15f81375d8e524aa6a5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Eye and associated structures. 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We hypothesized that, analogous to the finding that motor imagery increases the excitability of motor cortex, visual imagery should increase visual cortex excitability, as indexed by a decrease in the phosphene threshold (PT). In order to test visual cortex excitability, the primary visual cortex was stimulated with transcranial magnetic stimulation (TMS), so as to elicite phosphenes in the right lower visual quadrant. Subjects performed a visual imagery task and an auditory control task. We applied TMS with increasing intensity to determine the PT for each subject. Independent of the quadrant in which subjects placed their visual images, imagery decreased PT compared to baseline PT; in contrast, the auditory task did not change PT. These findings demonstrate for the first time a short-term, task-dependent modulation of PT. 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| subjects | Adult Biological and medical sciences Eye and associated structures. Visual pathways and centers. Vision Female Fundamental and applied biological sciences. Psychology Humans Imagery (Psychotherapy) Magnetics Male Phosphene threshold Phosphenes Primary visual cortex Reference Values Space life sciences Transcranial magnetic stimulation Vertebrates: nervous system and sense organs Visual Cortex - physiology Visual mental imagery |
| title | Visual cortex excitability increases during visual mental imagery—a TMS study in healthy human subjects |
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