The effects of OP-1206 α-CD on walking dysfunction in the rat neuropathic intermittent claudication model

IV prostaglandin E1 improves clinical symptoms in patients with spinal canal stenosis. In the present study, we assessed the effects of OP-1206 alpha-CD, an orally active prostaglandin E1 analog, on walking dysfunction in the rat neuropathic intermittent claudication model. To induce spinal stenosis...

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Veröffentlicht in:	Anesthesia and analgesia 2002-06, Vol.94 (6), p.1537-1541
Hauptverfasser:	NAKAI, Katsuhiko, TAKENOBU, Yoshifumi, EGUCHI, Kazuhide, TAKIMIZU, Hideyuki, HONJO, Kaneyoshi, AKIMARU, Shinji, MAEGAWA, Hitoshi, MARSALA, Martin, KATSUBE, Nobuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alprostadil - analogs & derivatives Alprostadil - therapeutic use Animals Biological and medical sciences Cardiovascular system Intermittent Claudication - drug therapy Male Medical sciences Pharmacology. Drug treatments Platelet Aggregation Inhibitors - pharmacology Prostaglandins E, Synthetic - therapeutic use Rats Rats, Wistar Regional Blood Flow - drug effects Skin - blood supply Skin - drug effects Spinal Cord - blood supply Spinal Cord - drug effects Spinal Stenosis - physiopathology Vasodilator Agents - pharmacology Vasodilator Agents - therapeutic use Vasodilator agents. Cerebral vasodilators Walking - physiology
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