New evidence for the selective, long-lasting central effects of the brain-targeted estradiol, Estredox

The present study examined the dose- and time-dependent central effects of an estradiol chemical delivery system cyclodextrin complex (E 2-CDS–CD) on the reestablishment of copulatory behavior of castrated male and ovariectomized female rats with concomitant determination of the blood luteinizing ho...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2004-03, Vol.77 (3), p.423-429
Hauptverfasser:	Tapfer, Mariann K, Sebestyen, Laszlo, Kurucz, Istvan, Horvath, Katalin, Szelenyi, Istvan, Bodor, Nicholas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain - drug effects Brain - metabolism Brain targeting Castration Central vs. peripheral effect Copulatory behavior Dose-Response Relationship, Drug Estradiol Estradiol - analogs & derivatives Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Lordosis behavior Luteinizing Hormone - blood Male Medical sciences Neuropharmacology Orchiectomy Ovariectomy Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Sexual Behavior, Animal - drug effects Sexual Behavior, Animal - physiology Time
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