Identification of Naive or Antigen-Experienced Human CD8+ T Cells by Expression of Costimulation and Chemokine Receptors: Analysis of the Human Cytomegalovirus-Specific CD8+ T Cell Response

Human CMV (HCMV) infection provides an informative model of how long term human CD8(+) T cell memory is maintained in the presence of Ag. To clarify the phenotypic identity of Ag-experienced human CD8(+) T cells in vivo, we determined the expression of costimulation and chemokine receptors on Ag-spe...

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Veröffentlicht in:	The Journal of immunology (1950) 2002-06, Vol.168 (11), p.5455-5464
Hauptverfasser:	Wills, Mark R, Okecha, Georgina, Weekes, Michael P, Gandhi, Maher K, Sissons, Patrick J. G, Carmichael, Andrew J
Format:	Artikel
Sprache:	eng
Schlagworte:	CD28 Antigens - analysis CD8-Positive T-Lymphocytes - chemistry CD8-Positive T-Lymphocytes - immunology Cell Differentiation Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Humans Leukocyte Common Antigens - analysis Phosphoproteins - immunology Receptors, CCR7 Receptors, Chemokine - analysis Tumor Necrosis Factor Receptor Superfamily, Member 7 - analysis Viral Matrix Proteins - immunology
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