Endovascular Aortic Aneurysm Repair in the Octogenarian: Is It Worthwhile?
HYPOTHESIS During the past decade, endovascular stent graft repair (EVSG) of abdominal aortic aneurysms has emerged as a less invasive and less morbid alternative to open surgical repair. We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years. DESIGN Re...
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creator | Minor, Michael E Ellozy, Sharif Carroccio, Alfio Oak, Juliana Chae, Kristina Agarwal, Gautam Surmay, Ryan Teodorescu, Victoria Morrissey, Nicholas J Jacobs, Tikva Lookstein, Robert Hollier, Larry H Marin, Michael L |
description | HYPOTHESIS During the past decade, endovascular stent graft repair (EVSG) of abdominal aortic aneurysms has emerged as a less invasive and less morbid alternative to open surgical repair. We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years. DESIGN Retrospective case series. SETTING Major academic medical center with extensive experience in endovascular and open aortic aneurysm surgery. PATIENTS AND METHODS During a 5-year period, EVSG was performed in 595 patients at our institution. One hundred fifty (25.2%) of these patients were older than 80 years. Our prospectively acquired database was reviewed with respect to the demographic, intraoperative, and outcome data of this elderly population. MAIN OUTCOME MEASURES Technical and clinical success, aneurysm-related events (aneurysm-related death, type I or type III endoleaks, aneurysm expansion, or aneurysm rupture), and secondary interventions. RESULTS There were 119 men (79.3%) and 31 women (20.7%) (mean age, 84.6 years). Mean aneurysm diameter was 6.7 cm. Comorbidities including chronic obstructive pulmonary disease, coronary artery disease, chronic renal insufficiency, peripheral vascular disease, hypertension, and hypercholesterolemia were common in these patients, with an average of 2.9 comorbid conditions per patient. Mean follow-up was 16.9 months (range, 1.0-61.4 months). One hundred forty-six patients (97.3%) received only regional anesthesia, and the average intraoperative blood loss was 369 mL. Average hospital and intensive care unit stays were 2.5 days and 0.1 day, respectively. The procedure was performed emergently in 3 patients, and each recovered uneventfully. There were 5 aborted procedures (3.3%) for technical reasons and 4 conversions to open aortic repair (2.6%). In addition to these aborted procedures, there were 2 additional technical failures resulting in a technical success rate of 95.3%. Endoleaks were common and included 9 type I (6.90%), 35 type II (24.10%), and 1 type III (0.69%). The majority either resolved spontaneously (type IIs) or with minimally invasive secondary intervention, which was performed in 13 patients. Perioperative local/vascular and systemic complications occurred in 16 (10.7%) and 8 (5.3%) patients, respectively. There were 5 perioperative deaths (3.3%)(30 days postoperatively) occurred, which were unrelated to the EVSG procedure. CONCLUSIONS Endovascular re |
doi_str_mv | 10.1001/archsurg.139.3.308 |
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We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years. DESIGN Retrospective case series. SETTING Major academic medical center with extensive experience in endovascular and open aortic aneurysm surgery. PATIENTS AND METHODS During a 5-year period, EVSG was performed in 595 patients at our institution. One hundred fifty (25.2%) of these patients were older than 80 years. Our prospectively acquired database was reviewed with respect to the demographic, intraoperative, and outcome data of this elderly population. MAIN OUTCOME MEASURES Technical and clinical success, aneurysm-related events (aneurysm-related death, type I or type III endoleaks, aneurysm expansion, or aneurysm rupture), and secondary interventions. RESULTS There were 119 men (79.3%) and 31 women (20.7%) (mean age, 84.6 years). Mean aneurysm diameter was 6.7 cm. Comorbidities including chronic obstructive pulmonary disease, coronary artery disease, chronic renal insufficiency, peripheral vascular disease, hypertension, and hypercholesterolemia were common in these patients, with an average of 2.9 comorbid conditions per patient. Mean follow-up was 16.9 months (range, 1.0-61.4 months). One hundred forty-six patients (97.3%) received only regional anesthesia, and the average intraoperative blood loss was 369 mL. Average hospital and intensive care unit stays were 2.5 days and 0.1 day, respectively. The procedure was performed emergently in 3 patients, and each recovered uneventfully. There were 5 aborted procedures (3.3%) for technical reasons and 4 conversions to open aortic repair (2.6%). In addition to these aborted procedures, there were 2 additional technical failures resulting in a technical success rate of 95.3%. Endoleaks were common and included 9 type I (6.90%), 35 type II (24.10%), and 1 type III (0.69%). The majority either resolved spontaneously (type IIs) or with minimally invasive secondary intervention, which was performed in 13 patients. Perioperative local/vascular and systemic complications occurred in 16 (10.7%) and 8 (5.3%) patients, respectively. There were 5 perioperative deaths (3.3%)(<30 days postoperatively). Forty late deaths (26.7%)(>30 days postoperatively) occurred, which were unrelated to the EVSG procedure. CONCLUSIONS Endovascular repair of abdominal aortic aneurysms can be performed safely and successfully in the majority of octogenarians with relatively low complication rates. Improved EVSG devices and operator experience may make this procedure the treatment method of choice for patients in this age group who meet specific anatomical criteria.Arch Surg 2004;139:308-314--></description><identifier>ISSN: 0004-0010</identifier><identifier>EISSN: 1538-3644</identifier><identifier>DOI: 10.1001/archsurg.139.3.308</identifier><identifier>PMID: 15006890</identifier><identifier>CODEN: ARSUAX</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal - surgery ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Vessel Prosthesis Implantation ; Cardiology. Vascular system ; Diseases of the aorta ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Female ; General aspects ; Humans ; Male ; Medical sciences ; Patient Selection ; Prosthesis Failure ; Statistics, Nonparametric ; Stents ; Survival Analysis ; Treatment Outcome</subject><ispartof>Archives of surgery (Chicago. 1960), 2004-03, Vol.139 (3), p.308-314</ispartof><rights>2004 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamasurgery/articlepdf/10.1001/archsurg.139.3.308$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/archsurg.139.3.308$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,776,780,3326,27903,27904,76236,76239</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15611160$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15006890$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Minor, Michael E</creatorcontrib><creatorcontrib>Ellozy, Sharif</creatorcontrib><creatorcontrib>Carroccio, Alfio</creatorcontrib><creatorcontrib>Oak, Juliana</creatorcontrib><creatorcontrib>Chae, Kristina</creatorcontrib><creatorcontrib>Agarwal, Gautam</creatorcontrib><creatorcontrib>Surmay, Ryan</creatorcontrib><creatorcontrib>Teodorescu, Victoria</creatorcontrib><creatorcontrib>Morrissey, Nicholas J</creatorcontrib><creatorcontrib>Jacobs, Tikva</creatorcontrib><creatorcontrib>Lookstein, Robert</creatorcontrib><creatorcontrib>Hollier, Larry H</creatorcontrib><creatorcontrib>Marin, Michael L</creatorcontrib><title>Endovascular Aortic Aneurysm Repair in the Octogenarian: Is It Worthwhile?</title><title>Archives of surgery (Chicago. 1960)</title><addtitle>Arch Surg</addtitle><description>HYPOTHESIS During the past decade, endovascular stent graft repair (EVSG) of abdominal aortic aneurysms has emerged as a less invasive and less morbid alternative to open surgical repair. We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years. DESIGN Retrospective case series. SETTING Major academic medical center with extensive experience in endovascular and open aortic aneurysm surgery. PATIENTS AND METHODS During a 5-year period, EVSG was performed in 595 patients at our institution. One hundred fifty (25.2%) of these patients were older than 80 years. Our prospectively acquired database was reviewed with respect to the demographic, intraoperative, and outcome data of this elderly population. MAIN OUTCOME MEASURES Technical and clinical success, aneurysm-related events (aneurysm-related death, type I or type III endoleaks, aneurysm expansion, or aneurysm rupture), and secondary interventions. RESULTS There were 119 men (79.3%) and 31 women (20.7%) (mean age, 84.6 years). Mean aneurysm diameter was 6.7 cm. Comorbidities including chronic obstructive pulmonary disease, coronary artery disease, chronic renal insufficiency, peripheral vascular disease, hypertension, and hypercholesterolemia were common in these patients, with an average of 2.9 comorbid conditions per patient. Mean follow-up was 16.9 months (range, 1.0-61.4 months). One hundred forty-six patients (97.3%) received only regional anesthesia, and the average intraoperative blood loss was 369 mL. Average hospital and intensive care unit stays were 2.5 days and 0.1 day, respectively. The procedure was performed emergently in 3 patients, and each recovered uneventfully. There were 5 aborted procedures (3.3%) for technical reasons and 4 conversions to open aortic repair (2.6%). In addition to these aborted procedures, there were 2 additional technical failures resulting in a technical success rate of 95.3%. Endoleaks were common and included 9 type I (6.90%), 35 type II (24.10%), and 1 type III (0.69%). The majority either resolved spontaneously (type IIs) or with minimally invasive secondary intervention, which was performed in 13 patients. Perioperative local/vascular and systemic complications occurred in 16 (10.7%) and 8 (5.3%) patients, respectively. There were 5 perioperative deaths (3.3%)(<30 days postoperatively). Forty late deaths (26.7%)(>30 days postoperatively) occurred, which were unrelated to the EVSG procedure. CONCLUSIONS Endovascular repair of abdominal aortic aneurysms can be performed safely and successfully in the majority of octogenarians with relatively low complication rates. Improved EVSG devices and operator experience may make this procedure the treatment method of choice for patients in this age group who meet specific anatomical criteria.Arch Surg 2004;139:308-314--></description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Aneurysm, Abdominal - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Vessel Prosthesis Implantation</subject><subject>Cardiology. Vascular system</subject><subject>Diseases of the aorta</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Patient Selection</subject><subject>Prosthesis Failure</subject><subject>Statistics, Nonparametric</subject><subject>Stents</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><issn>0004-0010</issn><issn>1538-3644</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpN0E1LAzEQgOEgitaPP-BBctHb1plNNpv1IqVUrRQEUTyGaZralf2oya7ivzfSip4ykGfm8DJ2ijBEALwkb1eh969DFMVQDAXoHTbATOhEKCl32QAAZBIlHLDDEN7ilOoi3WcHmAEoXcCA3U-aRftBwfYVeT5qfVdaPmpc779CzR_dmkrPy4Z3K8cfbNe-uoZ8Sc0VnwY-7fhL3Fh9rsrKXR-zvSVVwZ1s3yP2fDN5Gt8ls4fb6Xg0S0gAdgllKnOUpi6fK2mhKJTSuVxokFBIlJARFaTkXJIgi0pD9JZclufSFsKm4ohdbO6uffveu9CZugzWVRU1ru2DyTGHXANGmG6g9W0I3i3N2pc1-S-DYH4Kmt-CJhY0wsSCcelse72f127xt7JNFsH5FsRqVC09NbYM_5xCRPXjTjeOavr7RRAaU_ENoxGCNw</recordid><startdate>20040301</startdate><enddate>20040301</enddate><creator>Minor, Michael E</creator><creator>Ellozy, Sharif</creator><creator>Carroccio, Alfio</creator><creator>Oak, Juliana</creator><creator>Chae, Kristina</creator><creator>Agarwal, Gautam</creator><creator>Surmay, Ryan</creator><creator>Teodorescu, Victoria</creator><creator>Morrissey, Nicholas J</creator><creator>Jacobs, Tikva</creator><creator>Lookstein, Robert</creator><creator>Hollier, Larry H</creator><creator>Marin, Michael L</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040301</creationdate><title>Endovascular Aortic Aneurysm Repair in the Octogenarian: Is It Worthwhile?</title><author>Minor, Michael E ; Ellozy, Sharif ; Carroccio, Alfio ; Oak, Juliana ; Chae, Kristina ; Agarwal, Gautam ; Surmay, Ryan ; Teodorescu, Victoria ; Morrissey, Nicholas J ; Jacobs, Tikva ; Lookstein, Robert ; Hollier, Larry H ; Marin, Michael L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a301t-a565ea22e7b64c09966874d8040941405aa9a64b4a3ac1680565cae5774c93c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Aneurysm, Abdominal - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Vessel Prosthesis Implantation</topic><topic>Cardiology. Vascular system</topic><topic>Diseases of the aorta</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Patient Selection</topic><topic>Prosthesis Failure</topic><topic>Statistics, Nonparametric</topic><topic>Stents</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><toplevel>online_resources</toplevel><creatorcontrib>Minor, Michael E</creatorcontrib><creatorcontrib>Ellozy, Sharif</creatorcontrib><creatorcontrib>Carroccio, Alfio</creatorcontrib><creatorcontrib>Oak, Juliana</creatorcontrib><creatorcontrib>Chae, Kristina</creatorcontrib><creatorcontrib>Agarwal, Gautam</creatorcontrib><creatorcontrib>Surmay, Ryan</creatorcontrib><creatorcontrib>Teodorescu, Victoria</creatorcontrib><creatorcontrib>Morrissey, Nicholas J</creatorcontrib><creatorcontrib>Jacobs, Tikva</creatorcontrib><creatorcontrib>Lookstein, Robert</creatorcontrib><creatorcontrib>Hollier, Larry H</creatorcontrib><creatorcontrib>Marin, Michael L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of surgery (Chicago. 1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Minor, Michael E</au><au>Ellozy, Sharif</au><au>Carroccio, Alfio</au><au>Oak, Juliana</au><au>Chae, Kristina</au><au>Agarwal, Gautam</au><au>Surmay, Ryan</au><au>Teodorescu, Victoria</au><au>Morrissey, Nicholas J</au><au>Jacobs, Tikva</au><au>Lookstein, Robert</au><au>Hollier, Larry H</au><au>Marin, Michael L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endovascular Aortic Aneurysm Repair in the Octogenarian: Is It Worthwhile?</atitle><jtitle>Archives of surgery (Chicago. 1960)</jtitle><addtitle>Arch Surg</addtitle><date>2004-03-01</date><risdate>2004</risdate><volume>139</volume><issue>3</issue><spage>308</spage><epage>314</epage><pages>308-314</pages><issn>0004-0010</issn><eissn>1538-3644</eissn><coden>ARSUAX</coden><abstract>HYPOTHESIS During the past decade, endovascular stent graft repair (EVSG) of abdominal aortic aneurysms has emerged as a less invasive and less morbid alternative to open surgical repair. We hypothesize that EVSG may become the treatment method of choice among patients older than 80 years. DESIGN Retrospective case series. SETTING Major academic medical center with extensive experience in endovascular and open aortic aneurysm surgery. PATIENTS AND METHODS During a 5-year period, EVSG was performed in 595 patients at our institution. One hundred fifty (25.2%) of these patients were older than 80 years. Our prospectively acquired database was reviewed with respect to the demographic, intraoperative, and outcome data of this elderly population. MAIN OUTCOME MEASURES Technical and clinical success, aneurysm-related events (aneurysm-related death, type I or type III endoleaks, aneurysm expansion, or aneurysm rupture), and secondary interventions. RESULTS There were 119 men (79.3%) and 31 women (20.7%) (mean age, 84.6 years). Mean aneurysm diameter was 6.7 cm. Comorbidities including chronic obstructive pulmonary disease, coronary artery disease, chronic renal insufficiency, peripheral vascular disease, hypertension, and hypercholesterolemia were common in these patients, with an average of 2.9 comorbid conditions per patient. Mean follow-up was 16.9 months (range, 1.0-61.4 months). One hundred forty-six patients (97.3%) received only regional anesthesia, and the average intraoperative blood loss was 369 mL. Average hospital and intensive care unit stays were 2.5 days and 0.1 day, respectively. The procedure was performed emergently in 3 patients, and each recovered uneventfully. There were 5 aborted procedures (3.3%) for technical reasons and 4 conversions to open aortic repair (2.6%). In addition to these aborted procedures, there were 2 additional technical failures resulting in a technical success rate of 95.3%. Endoleaks were common and included 9 type I (6.90%), 35 type II (24.10%), and 1 type III (0.69%). The majority either resolved spontaneously (type IIs) or with minimally invasive secondary intervention, which was performed in 13 patients. Perioperative local/vascular and systemic complications occurred in 16 (10.7%) and 8 (5.3%) patients, respectively. There were 5 perioperative deaths (3.3%)(<30 days postoperatively). Forty late deaths (26.7%)(>30 days postoperatively) occurred, which were unrelated to the EVSG procedure. CONCLUSIONS Endovascular repair of abdominal aortic aneurysms can be performed safely and successfully in the majority of octogenarians with relatively low complication rates. Improved EVSG devices and operator experience may make this procedure the treatment method of choice for patients in this age group who meet specific anatomical criteria.Arch Surg 2004;139:308-314--></abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>15006890</pmid><doi>10.1001/archsurg.139.3.308</doi><tpages>7</tpages></addata></record> |
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subjects | Age Factors Aged Aged, 80 and over Aortic Aneurysm, Abdominal - surgery Biological and medical sciences Blood and lymphatic vessels Blood Vessel Prosthesis Implantation Cardiology. Vascular system Diseases of the aorta Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female General aspects Humans Male Medical sciences Patient Selection Prosthesis Failure Statistics, Nonparametric Stents Survival Analysis Treatment Outcome |
title | Endovascular Aortic Aneurysm Repair in the Octogenarian: Is It Worthwhile? |
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