Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves

Matrix metalloproteinases are endopeptidases that function in cell matrix turnover. Abnormal matrix metalloproteinase activity has been implicated in the formation of atherosclerotic abdominal aortic aneurysms. Recent studies suggest that abnormal matrix metalloproteinase activity may also be associ...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2004-03, Vol.127 (3), p.686-691
Hauptverfasser:	Boyum, Jon, Fellinger, Erika K, Schmoker, Joseph D, Trombley, Lucy, McPartland, Kenneth, Ittleman, Frank P, Howard, Alan B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Aorta, Thoracic - enzymology Aortic Aneurysm, Thoracic - complications Aortic Aneurysm, Thoracic - enzymology Aortic Valve - abnormalities Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava Diseases of the aorta Female Heart Humans Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Medical sciences Middle Aged Pneumology Tissue Inhibitor of Metalloproteinase-1 - metabolism Tissue Inhibitor of Metalloproteinase-2 - metabolism
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