Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?
Study design: A cross-sectional study evaluating BMD at the hip and tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals. Objectives: To investigate the speed of sound (SOS) in bone in relation to bone mineral density (BMD). Se...
Gespeichert in:
| Veröffentlicht in: | Spinal cord 2004-03, Vol.42 (3), p.141-145 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 145 |
|---|---|
| container_issue | 3 |
| container_start_page | 141 |
| container_title | Spinal cord |
| container_volume | 42 |
| creator | Giangregorio, L M Webber, C E |
| description | Study design:
A cross-sectional study evaluating BMD at the hip and tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals.
Objectives:
To investigate the speed of sound (SOS) in bone in relation to bone mineral density (BMD).
Setting:
Kinesiology Department, McMaster University, Ontario, Canada.
Methods:
In 14 individuals with SCI and 10 non-SCI individuals, proximal femur and tibia BMD were measured using dual energy X-ray absorptiometry, and radius and tibia SOS were measured with an ultrasonometer.
T
-scores were calculated using healthy reference databases. Inter-relationships between measurement techniques were determined using Pearson's correlation coefficients.
P
-values less than 0.05 were considered statistically significant.
Results:
The average ages of the SCI and non-SCI groups were 33±9 and 27±6 years, respectively. Lesion level ranged from C4 to T12 and average time postinjury was 12 years, with a range of 1.6–25 years. Using the WHO criteria for osteoporosis, nine of 14 SCI subjects were osteoporotic at the hip, with the remainder in the osteopenic range. Tibia SOS
T
-scores were in the osteoporotic range for one subject with SCI, and two were in the osteopenic range. Among non-SCI individuals, one male had a tibia SOS
T
-score of −1.4, all others were within the normal range. Hip BMD and tibia SOS were significantly correlated (
r
=0.46,
P |
| doi_str_mv | 10.1038/sj.sc.3101570 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71702060</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71702060</sourcerecordid><originalsourceid>FETCH-LOGICAL-c446t-c6e0bbd1de27ad689812a107122cb5ada74236c284a29c2a7f1ce3163b302c673</originalsourceid><addsrcrecordid>eNp10cuL1TAUB-AiivPQpUslCOOu1zzapJ2NyOBjYMCFui5pcqopbXLNSZX735tLqzMMzOoEzpdfHqcoXjC6Y1Q0b3HcodkJRlmt6KPilFVKlrXk1eO8FpKXlWjFSXGGOFJKW9Y2T4sTVlPKWtWcFoevewBLwkAwLN4S50kfPBCdSPoJJLne6UvikLhEIkw6ZZwCmcIfiGRyc7_y2XmIeiIWPLp0OMbg3nk9lSZEWzo_LhGO6db9dnbRE757VjwZcoXnWz0vvn_88O3qc3nz5dP11fub0lSVTKWRQPveMgtcaSubtmFcM6oY56avtdWq4kIa3lSat4ZrNTADgknRC8qNVOK8eLPm7mP4tQCmbnZoYJq0h7Bgp5iinEqa4et7cAxLzG_AjvNWNA1XdUblikwMiBGGbh_drOOhY7Q7DqTDsUPTbQPJ_tUWuvQz2Fu9TSCDiw1oNHoaovbG4R0nRVtxmd1udZhb_gfE29s9dPLLdYPXKX_-_8R__b-yfays</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>229388275</pqid></control><display><type>article</type><title>Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Giangregorio, L M ; Webber, C E</creator><creatorcontrib>Giangregorio, L M ; Webber, C E</creatorcontrib><description>Study design:
A cross-sectional study evaluating BMD at the hip and tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals.
Objectives:
To investigate the speed of sound (SOS) in bone in relation to bone mineral density (BMD).
Setting:
Kinesiology Department, McMaster University, Ontario, Canada.
Methods:
In 14 individuals with SCI and 10 non-SCI individuals, proximal femur and tibia BMD were measured using dual energy X-ray absorptiometry, and radius and tibia SOS were measured with an ultrasonometer.
T
-scores were calculated using healthy reference databases. Inter-relationships between measurement techniques were determined using Pearson's correlation coefficients.
P
-values less than 0.05 were considered statistically significant.
Results:
The average ages of the SCI and non-SCI groups were 33±9 and 27±6 years, respectively. Lesion level ranged from C4 to T12 and average time postinjury was 12 years, with a range of 1.6–25 years. Using the WHO criteria for osteoporosis, nine of 14 SCI subjects were osteoporotic at the hip, with the remainder in the osteopenic range. Tibia SOS
T
-scores were in the osteoporotic range for one subject with SCI, and two were in the osteopenic range. Among non-SCI individuals, one male had a tibia SOS
T
-score of −1.4, all others were within the normal range. Hip BMD and tibia SOS were significantly correlated (
r
=0.46,
P
<0.01). Hip BMD and tibia BMD were more strongly correlated (
r
=0.80,
P
<0.0005). Tibia BMD was not significantly correlated with SOS at the tibia (
r
=0.35,
P
=0.09). Radius SOS
T
-scores were positive and not significantly correlated with any lower limb variable.
Conclusion:
Lower-limb bone mass is reduced in spinal cord-injured individuals, but SOS at the mid-tibia is not. It remains to be determined whether ultrasound measurements can predict fracture in the SCI population.</description><identifier>ISSN: 1362-4393</identifier><identifier>EISSN: 1476-5624</identifier><identifier>DOI: 10.1038/sj.sc.3101570</identifier><identifier>PMID: 15001978</identifier><identifier>CODEN: SPCOFM</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Absorptiometry, Photon ; Adult ; Anatomy ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Bone and Bones - physiology ; Bone Density - physiology ; Cerebrospinal fluid. Meninges. Spinal cord ; Cross-Sectional Studies ; Female ; Hip - physiology ; Human Physiology ; Humans ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurochemistry ; Neurology ; Neuropsychology ; Neurosciences ; original-article ; Osteoporosis - diagnosis ; Radius - physiology ; Spinal Cord Injuries - physiopathology ; Tibia - physiology ; Ultrasonography</subject><ispartof>Spinal cord, 2004-03, Vol.42 (3), p.141-145</ispartof><rights>Springer Nature Limited 2004</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Nature Publishing Group Mar 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-c6e0bbd1de27ad689812a107122cb5ada74236c284a29c2a7f1ce3163b302c673</citedby><cites>FETCH-LOGICAL-c446t-c6e0bbd1de27ad689812a107122cb5ada74236c284a29c2a7f1ce3163b302c673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15639426$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15001978$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giangregorio, L M</creatorcontrib><creatorcontrib>Webber, C E</creatorcontrib><title>Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?</title><title>Spinal cord</title><addtitle>Spinal Cord</addtitle><addtitle>Spinal Cord</addtitle><description>Study design:
A cross-sectional study evaluating BMD at the hip and tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals.
Objectives:
To investigate the speed of sound (SOS) in bone in relation to bone mineral density (BMD).
Setting:
Kinesiology Department, McMaster University, Ontario, Canada.
Methods:
In 14 individuals with SCI and 10 non-SCI individuals, proximal femur and tibia BMD were measured using dual energy X-ray absorptiometry, and radius and tibia SOS were measured with an ultrasonometer.
T
-scores were calculated using healthy reference databases. Inter-relationships between measurement techniques were determined using Pearson's correlation coefficients.
P
-values less than 0.05 were considered statistically significant.
Results:
The average ages of the SCI and non-SCI groups were 33±9 and 27±6 years, respectively. Lesion level ranged from C4 to T12 and average time postinjury was 12 years, with a range of 1.6–25 years. Using the WHO criteria for osteoporosis, nine of 14 SCI subjects were osteoporotic at the hip, with the remainder in the osteopenic range. Tibia SOS
T
-scores were in the osteoporotic range for one subject with SCI, and two were in the osteopenic range. Among non-SCI individuals, one male had a tibia SOS
T
-score of −1.4, all others were within the normal range. Hip BMD and tibia SOS were significantly correlated (
r
=0.46,
P
<0.01). Hip BMD and tibia BMD were more strongly correlated (
r
=0.80,
P
<0.0005). Tibia BMD was not significantly correlated with SOS at the tibia (
r
=0.35,
P
=0.09). Radius SOS
T
-scores were positive and not significantly correlated with any lower limb variable.
Conclusion:
Lower-limb bone mass is reduced in spinal cord-injured individuals, but SOS at the mid-tibia is not. It remains to be determined whether ultrasound measurements can predict fracture in the SCI population.</description><subject>Absorptiometry, Photon</subject><subject>Adult</subject><subject>Anatomy</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bone and Bones - physiology</subject><subject>Bone Density - physiology</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Hip - physiology</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurochemistry</subject><subject>Neurology</subject><subject>Neuropsychology</subject><subject>Neurosciences</subject><subject>original-article</subject><subject>Osteoporosis - diagnosis</subject><subject>Radius - physiology</subject><subject>Spinal Cord Injuries - physiopathology</subject><subject>Tibia - physiology</subject><subject>Ultrasonography</subject><issn>1362-4393</issn><issn>1476-5624</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp10cuL1TAUB-AiivPQpUslCOOu1zzapJ2NyOBjYMCFui5pcqopbXLNSZX735tLqzMMzOoEzpdfHqcoXjC6Y1Q0b3HcodkJRlmt6KPilFVKlrXk1eO8FpKXlWjFSXGGOFJKW9Y2T4sTVlPKWtWcFoevewBLwkAwLN4S50kfPBCdSPoJJLne6UvikLhEIkw6ZZwCmcIfiGRyc7_y2XmIeiIWPLp0OMbg3nk9lSZEWzo_LhGO6db9dnbRE757VjwZcoXnWz0vvn_88O3qc3nz5dP11fub0lSVTKWRQPveMgtcaSubtmFcM6oY56avtdWq4kIa3lSat4ZrNTADgknRC8qNVOK8eLPm7mP4tQCmbnZoYJq0h7Bgp5iinEqa4et7cAxLzG_AjvNWNA1XdUblikwMiBGGbh_drOOhY7Q7DqTDsUPTbQPJ_tUWuvQz2Fu9TSCDiw1oNHoaovbG4R0nRVtxmd1udZhb_gfE29s9dPLLdYPXKX_-_8R__b-yfays</recordid><startdate>20040301</startdate><enddate>20040301</enddate><creator>Giangregorio, L M</creator><creator>Webber, C E</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20040301</creationdate><title>Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?</title><author>Giangregorio, L M ; Webber, C E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-c6e0bbd1de27ad689812a107122cb5ada74236c284a29c2a7f1ce3163b302c673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Absorptiometry, Photon</topic><topic>Adult</topic><topic>Anatomy</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bone and Bones - physiology</topic><topic>Bone Density - physiology</topic><topic>Cerebrospinal fluid. Meninges. Spinal cord</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Hip - physiology</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurochemistry</topic><topic>Neurology</topic><topic>Neuropsychology</topic><topic>Neurosciences</topic><topic>original-article</topic><topic>Osteoporosis - diagnosis</topic><topic>Radius - physiology</topic><topic>Spinal Cord Injuries - physiopathology</topic><topic>Tibia - physiology</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giangregorio, L M</creatorcontrib><creatorcontrib>Webber, C E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Spinal cord</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giangregorio, L M</au><au>Webber, C E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?</atitle><jtitle>Spinal cord</jtitle><stitle>Spinal Cord</stitle><addtitle>Spinal Cord</addtitle><date>2004-03-01</date><risdate>2004</risdate><volume>42</volume><issue>3</issue><spage>141</spage><epage>145</epage><pages>141-145</pages><issn>1362-4393</issn><eissn>1476-5624</eissn><coden>SPCOFM</coden><abstract>Study design:
A cross-sectional study evaluating BMD at the hip and tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals.
Objectives:
To investigate the speed of sound (SOS) in bone in relation to bone mineral density (BMD).
Setting:
Kinesiology Department, McMaster University, Ontario, Canada.
Methods:
In 14 individuals with SCI and 10 non-SCI individuals, proximal femur and tibia BMD were measured using dual energy X-ray absorptiometry, and radius and tibia SOS were measured with an ultrasonometer.
T
-scores were calculated using healthy reference databases. Inter-relationships between measurement techniques were determined using Pearson's correlation coefficients.
P
-values less than 0.05 were considered statistically significant.
Results:
The average ages of the SCI and non-SCI groups were 33±9 and 27±6 years, respectively. Lesion level ranged from C4 to T12 and average time postinjury was 12 years, with a range of 1.6–25 years. Using the WHO criteria for osteoporosis, nine of 14 SCI subjects were osteoporotic at the hip, with the remainder in the osteopenic range. Tibia SOS
T
-scores were in the osteoporotic range for one subject with SCI, and two were in the osteopenic range. Among non-SCI individuals, one male had a tibia SOS
T
-score of −1.4, all others were within the normal range. Hip BMD and tibia SOS were significantly correlated (
r
=0.46,
P
<0.01). Hip BMD and tibia BMD were more strongly correlated (
r
=0.80,
P
<0.0005). Tibia BMD was not significantly correlated with SOS at the tibia (
r
=0.35,
P
=0.09). Radius SOS
T
-scores were positive and not significantly correlated with any lower limb variable.
Conclusion:
Lower-limb bone mass is reduced in spinal cord-injured individuals, but SOS at the mid-tibia is not. It remains to be determined whether ultrasound measurements can predict fracture in the SCI population.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>15001978</pmid><doi>10.1038/sj.sc.3101570</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1362-4393 |
| ispartof | Spinal cord, 2004-03, Vol.42 (3), p.141-145 |
| issn | 1362-4393 1476-5624 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71702060 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Absorptiometry, Photon Adult Anatomy Biological and medical sciences Biomedical and Life Sciences Biomedicine Bone and Bones - physiology Bone Density - physiology Cerebrospinal fluid. Meninges. Spinal cord Cross-Sectional Studies Female Hip - physiology Human Physiology Humans Male Medical sciences Nervous system (semeiology, syndromes) Neurochemistry Neurology Neuropsychology Neurosciences original-article Osteoporosis - diagnosis Radius - physiology Spinal Cord Injuries - physiopathology Tibia - physiology Ultrasonography |
| title | Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T20%3A04%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Speed%20of%20sound%20in%20bone%20at%20the%20tibia:%20is%20it%20related%20to%20lower%20limb%20bone%20mineral%20density%20in%20spinal-cord-injured%20individuals?&rft.jtitle=Spinal%20cord&rft.au=Giangregorio,%20L%20M&rft.date=2004-03-01&rft.volume=42&rft.issue=3&rft.spage=141&rft.epage=145&rft.pages=141-145&rft.issn=1362-4393&rft.eissn=1476-5624&rft.coden=SPCOFM&rft_id=info:doi/10.1038/sj.sc.3101570&rft_dat=%3Cproquest_cross%3E71702060%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=229388275&rft_id=info:pmid/15001978&rfr_iscdi=true |