Photoaptamer arrays applied to multiplexed proteomic analysis

Multiplexed photoaptamer‐based arrays that allow for the simultaneous measurement of multiple proteins of interest in serum samples are described. Since photoaptamers covalently bind to their target analytes before fluorescent signal detection, the arrays can be vigorously washed to remove backgroun...

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Veröffentlicht in:	Proteomics (Weinheim) 2004-03, Vol.4 (3), p.609-618
Hauptverfasser:	Bock, Chris, Coleman, Mike, Collins, Brian, Davis, Jody, Foulds, Glenn, Gold, Larry, Greef, Chad, Heil, Jim, Heilig, Joseph S., Hicke, Brian, Nelson Hurst, Michele, Husar, Gregory M., Miller, Darcey, Ostroff, Rachel, Petach, Helen, Schneider, Dan, Vant-Hull, Barry, Waugh, Sheela, Weiss, Allison, Wilcox, Sheri K., Zichi, Dominic
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Antibodies - chemistry Aptamers Biological and medical sciences Colonic Neoplasms - diagnosis Colonic Neoplasms - metabolism Cross-Linking Reagents - chemistry Cross-Linking Reagents - pharmacology DNA - chemistry Dose-Response Relationship, Drug Endostatins - chemistry Endostatins - metabolism Fibroblast Growth Factor 2 - chemistry Fundamental and applied biological sciences. Psychology Humans Hydrogen-Ion Concentration Interleukin-16 - metabolism Kinetics Light Lod Score Miscellaneous Multiplex array Neoplasm Metastasis Oligonucleotides - chemistry Photoaptamer Protein Array Analysis - instrumentation Protein Array Analysis - methods Protein microarray Proteins Proteins - chemistry Proteomics - methods Tissue Inhibitor of Metalloproteinase-1 - chemistry Vascular Endothelial Growth Factor A - metabolism
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