Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding

Hypoxia is known to be an important prognostic marker in many human cancers. We report the use of two oxygen measurement techniques in human brain tumors and compare these data with semiquantitative histological end points. Oxygenation was measured using the Eppendorf needle electrode and/or EF5 bin...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2004-03, Vol.64 (5), p.1886-1892
Hauptverfasser:	EVANS, Sydney M, JUDY, Kevin D, JUDKINS, Alexander R, PHILLIPS, Peter, GEOERGER, Birgit, KOCH, Cameron J, DUNPHY, Isolde, JENKINS, W. Timothy, NELSON, Peter T, COLLINS, Ruth, WILEYTO, E. Paul, JENKINS, Kevin, HAHN, Stephen M, STEVENS, Craig W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Biological and medical sciences Brain Neoplasms - metabolism Cell Hypoxia Electrodes Etanidazole - analogs & derivatives Etanidazole - metabolism Humans Hydrocarbons, Fluorinated - metabolism Medical sciences Middle Aged Needles Oxygen - analysis Pharmacology. Drug treatments Tumors
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