In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis
This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subf...
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| Veröffentlicht in: | Journal of agricultural and food chemistry 2004-03, Vol.52 (5), p.1132-1137 |
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| container_title | Journal of agricultural and food chemistry |
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| creator | Tepe, Bektaş Daferera, Dimitra Sökmen, Münevver Polissiou, Moschos Sökmen, Atalay |
| description | This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subfractions showed moderate activity and polar extracts remained almost inactive. GC-MS analysis of the oil resulted in the identification of 39 compounds, representing 93.7% of the oil; thymol (30.6%), carvacrol (26.1%), and p-cymene (13.0%) were the main components. The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene−linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 μg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents. Keywords: Antimicrobial activity; antioxidant activity; essential oil; methanol extract; Thymus eigii |
| doi_str_mv | 10.1021/jf035094l |
| format | Article |
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The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene−linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 μg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents. 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Psychology ; Gas Chromatography-Mass Spectrometry ; Lamiaceae - chemistry ; Linoleic Acid - chemistry ; Monoterpenes - analysis ; Oils, Volatile - chemistry ; Oils, Volatile - pharmacology ; Oxidation-Reduction ; Picrates ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Plant Oils - chemistry ; Plant Oils - pharmacology ; Thymol - analysis</subject><ispartof>Journal of agricultural and food chemistry, 2004-03, Vol.52 (5), p.1132-1137</ispartof><rights>Copyright © 2004 American Chemical Society</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a379t-e6f94d258a34f1b03fe202b5e7d54910efdae5d140f30f160d81c9a143b1858c3</citedby><cites>FETCH-LOGICAL-a379t-e6f94d258a34f1b03fe202b5e7d54910efdae5d140f30f160d81c9a143b1858c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jf035094l$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jf035094l$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>315,782,786,2769,27085,27933,27934,56747,56797</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15561220$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14995110$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tepe, Bektaş</creatorcontrib><creatorcontrib>Daferera, Dimitra</creatorcontrib><creatorcontrib>Sökmen, Münevver</creatorcontrib><creatorcontrib>Polissiou, Moschos</creatorcontrib><creatorcontrib>Sökmen, Atalay</creatorcontrib><title>In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis</title><title>Journal of agricultural and food chemistry</title><addtitle>J. Agric. Food Chem</addtitle><description>This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subfractions showed moderate activity and polar extracts remained almost inactive. GC-MS analysis of the oil resulted in the identification of 39 compounds, representing 93.7% of the oil; thymol (30.6%), carvacrol (26.1%), and p-cymene (13.0%) were the main components. The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene−linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 μg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents. Keywords: Antimicrobial activity; antioxidant activity; essential oil; methanol extract; Thymus eigii</description><subject>Anti-Bacterial Agents - analysis</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antioxidants - analysis</subject><subject>Antioxidants - pharmacology</subject><subject>Aroma and flavouring agent industries</subject><subject>beta Carotene - chemistry</subject><subject>Biological and medical sciences</subject><subject>Biphenyl Compounds</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>Lamiaceae - chemistry</subject><subject>Linoleic Acid - chemistry</subject><subject>Monoterpenes - analysis</subject><subject>Oils, Volatile - chemistry</subject><subject>Oils, Volatile - pharmacology</subject><subject>Oxidation-Reduction</subject><subject>Picrates</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Oils - chemistry</subject><subject>Plant Oils - pharmacology</subject><subject>Thymol - analysis</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0U1vEzEQBmALgWgoHPgDyBeQOGzq8a7345iWQKq2aqSmFerFmvXaxGE_iu1U6Z0fjptEzYWTpZnHo9E7hHwENgbG4WRlWCpYlbWvyAgEZ4kAKF-TEYvNpBQ5HJF33q8YY6Uo2FtyBFlVRcNG5O95T-9scAOd9MF2VrmhtthS7JttZdjYBvtAJyrYRxus9nQwNCw1nXqvI4j22rZ---EOnR3Wnk43waEKW7pYPnWxpO0va-nVmN4PS3RPVAc6H8_G9Bs-Wv-evDHYev1h_x6T2-_Txdksubz-cX42uUwwLaqQ6NxUWcNFiWlmoGap0ZzxWuiiEVkFTJsGtWggYyZlBnLWlKAqhCytoRSlSo_Jl93cBzf8WWsfZGe90m2LvY57ywLyquQcIvy6gzEO75028sHZLu4tgcnnyOVL5NF-2g9d151uDnKfcQSf9wC9wtY47JX1ByfigTh_dsnOWR_05qWP7rfMi7QQcjG_kRf51fy--DmTp4e5qLxcDWvXx-z-s-A_83ajuQ</recordid><startdate>20040310</startdate><enddate>20040310</enddate><creator>Tepe, Bektaş</creator><creator>Daferera, Dimitra</creator><creator>Sökmen, Münevver</creator><creator>Polissiou, Moschos</creator><creator>Sökmen, Atalay</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040310</creationdate><title>In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis</title><author>Tepe, Bektaş ; Daferera, Dimitra ; Sökmen, Münevver ; Polissiou, Moschos ; Sökmen, Atalay</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a379t-e6f94d258a34f1b03fe202b5e7d54910efdae5d140f30f160d81c9a143b1858c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Anti-Bacterial Agents - analysis</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antioxidants - analysis</topic><topic>Antioxidants - pharmacology</topic><topic>Aroma and flavouring agent industries</topic><topic>beta Carotene - chemistry</topic><topic>Biological and medical sciences</topic><topic>Biphenyl Compounds</topic><topic>Food industries</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>Lamiaceae - chemistry</topic><topic>Linoleic Acid - chemistry</topic><topic>Monoterpenes - analysis</topic><topic>Oils, Volatile - chemistry</topic><topic>Oils, Volatile - pharmacology</topic><topic>Oxidation-Reduction</topic><topic>Picrates</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Oils - chemistry</topic><topic>Plant Oils - pharmacology</topic><topic>Thymol - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tepe, Bektaş</creatorcontrib><creatorcontrib>Daferera, Dimitra</creatorcontrib><creatorcontrib>Sökmen, Münevver</creatorcontrib><creatorcontrib>Polissiou, Moschos</creatorcontrib><creatorcontrib>Sökmen, Atalay</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tepe, Bektaş</au><au>Daferera, Dimitra</au><au>Sökmen, Münevver</au><au>Polissiou, Moschos</au><au>Sökmen, Atalay</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2004-03-10</date><risdate>2004</risdate><volume>52</volume><issue>5</issue><spage>1132</spage><epage>1137</epage><pages>1132-1137</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subfractions showed moderate activity and polar extracts remained almost inactive. GC-MS analysis of the oil resulted in the identification of 39 compounds, representing 93.7% of the oil; thymol (30.6%), carvacrol (26.1%), and p-cymene (13.0%) were the main components. The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene−linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 μg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents. Keywords: Antimicrobial activity; antioxidant activity; essential oil; methanol extract; Thymus eigii</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>14995110</pmid><doi>10.1021/jf035094l</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Anti-Bacterial Agents - analysis Anti-Bacterial Agents - pharmacology Antioxidants - analysis Antioxidants - pharmacology Aroma and flavouring agent industries beta Carotene - chemistry Biological and medical sciences Biphenyl Compounds Food industries Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Lamiaceae - chemistry Linoleic Acid - chemistry Monoterpenes - analysis Oils, Volatile - chemistry Oils, Volatile - pharmacology Oxidation-Reduction Picrates Plant Extracts - chemistry Plant Extracts - pharmacology Plant Oils - chemistry Plant Oils - pharmacology Thymol - analysis |
| title | In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis |
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