Combined Effect of Vitamin E and Insulin on Cataracts of Diabetic Rats Fed a High Cholesterol Diet

In the present study we investigated the effects of a long-term treatment with vitamin E, an antioxidant vitamin, insulin or their combination on cataracts of streptozotocin (STZ)-induced diabetic rats fed a high cholesterol diet. Each rat was checked for cataracts at 0, 1, 2, 4, 8, 12 and 15 weeks...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2004, Vol.27(3), pp.338-344
Hauptverfasser:	Yoshida, Masumi, Kimura, Hitoshi, Kyuki, Kouhei, Ito, Mikio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - administration & dosage Antioxidants - therapeutic use Blood Glucose - drug effects Body Weight cataract Cataract - etiology Cataract - pathology Cataract - prevention & control Cholesterol - blood Cholesterol, Dietary - administration & dosage diabetes Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Drug Therapy, Combination Eating Eye - pathology hyperglycemia hyperlipidemia Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Insulin - administration & dosage Insulin - therapeutic use lipid peroxide Lipid Peroxides - blood Male Rats Rats, Sprague-Dawley Triglycerides - blood Vitamin E - administration & dosage Vitamin E - therapeutic use
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