Anti-Inflammatory Compounds of Plant Origin. Part II. Modulation of Pro-Inflammatory Cytokines, Chemokines and Adhesion Molecules

Abstract It has been widely shown that many plant-derived compounds present significant anti-inflammatory effects. For this reason, they represent potential molecules for the development of new drugs, especially designed for the treatment and/or control of chronic inflammatory states such as rheumat...

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Veröffentlicht in:Planta medica 2004-02, Vol.70 (2), p.93-103
Hauptverfasser: Calixto, João B., Campos, Maria M., Otuki, Michel F., Santos, Adair R.
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container_end_page 103
container_issue 2
container_start_page 93
container_title Planta medica
container_volume 70
creator Calixto, João B.
Campos, Maria M.
Otuki, Michel F.
Santos, Adair R.
description Abstract It has been widely shown that many plant-derived compounds present significant anti-inflammatory effects. For this reason, they represent potential molecules for the development of new drugs, especially designed for the treatment and/or control of chronic inflammatory states such as rheumatism, asthma, inflammatory bowel diseases, atherosclerosis, etc. This review focuses on the naturally-occurring compounds with anti-inflammatory properties and attempts to correlate their actions with the modulation of cytokines and associated intracellular signalling pathways; it continues the review published in the November, 2003 issue of Planta Medica.
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subjects Anti-Inflammatory Agents, Non-Steroidal - pharmacology
Biological and medical sciences
Cell Adhesion Molecules - drug effects
Chemokines - metabolism
Cytokines - drug effects
General pharmacology
Humans
Inflammation - immunology
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plants, Medicinal
Review
title Anti-Inflammatory Compounds of Plant Origin. Part II. Modulation of Pro-Inflammatory Cytokines, Chemokines and Adhesion Molecules
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