Liver Fatty Acid-Binding Protein Colocalizes with Peroxisome Proliferator Activated Receptor α and Enhances Ligand Distribution to Nuclei of Living Cells

Although it is hypothesized that long-chain fatty acyl CoAs (LCFA-CoAs) and long-chain fatty acids (LCFAs) regulate transcription in the nucleus, little is known regarding factors that determine the distribution of these ligands to nuclei of living cells. Immunofluorescence colocalization showed tha...

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Veröffentlicht in:	Biochemistry (Easton) 2004-03, Vol.43 (9), p.2484-2500
Hauptverfasser:	Huang, Huan, Starodub, Olga, McIntosh, Avery, Atshaves, Barbara P, Woldegiorgis, Gebre, Kier, Ann B, Schroeder, Friedhelm
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - analysis Acyl Coenzyme A - metabolism Animals Biomarkers - chemistry Boron Compounds - metabolism Carrier Proteins - biosynthesis Carrier Proteins - metabolism Cell Nucleus - chemistry Cell Nucleus - metabolism Cytoplasm - metabolism Fatty Acid-Binding Protein 7 Fatty Acid-Binding Proteins Fatty Acids - analysis Fatty Acids - metabolism Fibroblasts - chemistry Fibroblasts - metabolism Fluorescent Antibody Technique, Indirect Fluorescent Dyes - metabolism Hydrolysis L Cells (Cell Line) Ligands Liver - metabolism Mice Nerve Tissue Proteins Nuclear Envelope - metabolism Peroxisomes - metabolism Protein Binding Receptors, Cytoplasmic and Nuclear - metabolism Transcription Factors - metabolism Transfection
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