Establishment of transfer standard for holmium-166-DOTMP
The measurement of 166Ho, both as a chloride solution and as [ 166Ho]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylenephoonic acid (DOTMP), was examined for four models of radionuclide calibrators: Capintec CRC-35R (two chambers), Capintec 712MX, AtomLab 100 (two chambers), and a Capintec CRC-...
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| Veröffentlicht in: | Applied radiation and isotopes 2004-02, Vol.60 (2), p.505-510 |
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| creator | Cessna, J.T Zimmerman, B.E Unterweger, M.P Golas, D.B |
| description | The measurement of
166Ho, both as a chloride solution and as [
166Ho]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylenephoonic acid (DOTMP), was examined for four models of radionuclide calibrators: Capintec CRC-35R (two chambers), Capintec 712MX, AtomLab 100 (two chambers), and a Capintec CRC-12. Holmium-166 chloride was measured as 16
ml in 20-ml glass dose vials. Diagnostic imaging level [
166Ho]DOTMP solutions, nominally 400
MBq
g
−1, were measured as 12
ml in 20-ml dose vials. Finally, therapeutic level [
166Ho]DOTMP solutions, nominally 9
GBq
g
−1, were measured as aliquots of 100–500
μl in sealed plastic vials of 10-ml saline. Single calibration factors for each instrument manufacturer are recommended for 12–16-ml of either solution in 20-ml glass dose vials, (673±9)×10 and 72.7±0.7, for the Capintec and AtomLab models, respectively. Calibration factors recommended for the therapeutic dose geometry are (706±6)×10 and 68.7±1.3, for the Capintec and AtomLab models, respectively. The calibration factors recommended for an NIST 5-ml ampoule are (686±5)×10 and 70.9±0.4 for the Capintec and AtomLab models, respectively. |
| doi_str_mv | 10.1016/j.apradiso.2003.11.067 |
| format | Article |
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166Ho, both as a chloride solution and as [
166Ho]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylenephoonic acid (DOTMP), was examined for four models of radionuclide calibrators: Capintec CRC-35R (two chambers), Capintec 712MX, AtomLab 100 (two chambers), and a Capintec CRC-12. Holmium-166 chloride was measured as 16
ml in 20-ml glass dose vials. Diagnostic imaging level [
166Ho]DOTMP solutions, nominally 400
MBq
g
−1, were measured as 12
ml in 20-ml dose vials. Finally, therapeutic level [
166Ho]DOTMP solutions, nominally 9
GBq
g
−1, were measured as aliquots of 100–500
μl in sealed plastic vials of 10-ml saline. Single calibration factors for each instrument manufacturer are recommended for 12–16-ml of either solution in 20-ml glass dose vials, (673±9)×10 and 72.7±0.7, for the Capintec and AtomLab models, respectively. Calibration factors recommended for the therapeutic dose geometry are (706±6)×10 and 68.7±1.3, for the Capintec and AtomLab models, respectively. The calibration factors recommended for an NIST 5-ml ampoule are (686±5)×10 and 70.9±0.4 for the Capintec and AtomLab models, respectively.</description><identifier>ISSN: 0969-8043</identifier><identifier>EISSN: 1872-9800</identifier><identifier>DOI: 10.1016/j.apradiso.2003.11.067</identifier><identifier>PMID: 14987693</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Calibration - standards ; Holmium-166 ; Nuclear medicine ; Organometallic Compounds - analysis ; Organometallic Compounds - standards ; Organophosphorus Compounds - analysis ; Organophosphorus Compounds - standards ; Quality Control ; Radiometry - instrumentation ; Radiometry - methods ; Radiometry - standards ; Radionuclide calibrator ; Radiopharmaceuticals - analysis ; Radiopharmaceuticals - standards ; Reference Standards ; Reproducibility of Results ; Sensitivity and Specificity ; Specimen Handling - methods ; Specimen Handling - standards ; Transfer standard ; United States</subject><ispartof>Applied radiation and isotopes, 2004-02, Vol.60 (2), p.505-510</ispartof><rights>2003 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c364t-ea24c7d45680735d8f1e924ac6bea6c4cba5ba1aeaa945f45f37ab0cb2c2def13</citedby><cites>FETCH-LOGICAL-c364t-ea24c7d45680735d8f1e924ac6bea6c4cba5ba1aeaa945f45f37ab0cb2c2def13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.apradiso.2003.11.067$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14987693$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cessna, J.T</creatorcontrib><creatorcontrib>Zimmerman, B.E</creatorcontrib><creatorcontrib>Unterweger, M.P</creatorcontrib><creatorcontrib>Golas, D.B</creatorcontrib><title>Establishment of transfer standard for holmium-166-DOTMP</title><title>Applied radiation and isotopes</title><addtitle>Appl Radiat Isot</addtitle><description>The measurement of
166Ho, both as a chloride solution and as [
166Ho]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylenephoonic acid (DOTMP), was examined for four models of radionuclide calibrators: Capintec CRC-35R (two chambers), Capintec 712MX, AtomLab 100 (two chambers), and a Capintec CRC-12. Holmium-166 chloride was measured as 16
ml in 20-ml glass dose vials. Diagnostic imaging level [
166Ho]DOTMP solutions, nominally 400
MBq
g
−1, were measured as 12
ml in 20-ml dose vials. Finally, therapeutic level [
166Ho]DOTMP solutions, nominally 9
GBq
g
−1, were measured as aliquots of 100–500
μl in sealed plastic vials of 10-ml saline. Single calibration factors for each instrument manufacturer are recommended for 12–16-ml of either solution in 20-ml glass dose vials, (673±9)×10 and 72.7±0.7, for the Capintec and AtomLab models, respectively. Calibration factors recommended for the therapeutic dose geometry are (706±6)×10 and 68.7±1.3, for the Capintec and AtomLab models, respectively. The calibration factors recommended for an NIST 5-ml ampoule are (686±5)×10 and 70.9±0.4 for the Capintec and AtomLab models, respectively.</description><subject>Calibration - standards</subject><subject>Holmium-166</subject><subject>Nuclear medicine</subject><subject>Organometallic Compounds - analysis</subject><subject>Organometallic Compounds - standards</subject><subject>Organophosphorus Compounds - analysis</subject><subject>Organophosphorus Compounds - standards</subject><subject>Quality Control</subject><subject>Radiometry - instrumentation</subject><subject>Radiometry - methods</subject><subject>Radiometry - standards</subject><subject>Radionuclide calibrator</subject><subject>Radiopharmaceuticals - analysis</subject><subject>Radiopharmaceuticals - standards</subject><subject>Reference Standards</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Specimen Handling - methods</subject><subject>Specimen Handling - standards</subject><subject>Transfer standard</subject><subject>United States</subject><issn>0969-8043</issn><issn>1872-9800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1OwzAQhC0EoqXwClVO3BLsxHHiG6iUH6moHMrZ2tgb1VUSFztB4u1J1SKOSCvtYWd2NB8hc0YTRpm42yWw92BscElKaZYwllBRnJEpK4s0liWl52RKpZBxSXk2IVch7CilvJTpJZkwLstCyGxKymXooWps2LbY9ZGro95DF2r00XjoDHgT1c5HW9e0dmhjJkT8uN68vV-TixqagDenPSMfT8vN4iVerZ9fFw-rWGeC9zFCynVheC5KWmS5KWuGMuWgRYUgNNcV5BUwQADJ83qcrICK6irVqcGaZTNye_y79-5zwNCr1gaNTQMduiGogomxk8xGoTgKtXcheKzV3tsW_LdiVB2YqZ36ZaYOzBRjamQ2GuenhKFq0fzZTpBGwf1RgGPPL4teBW2x02isR90r4-x_GT_q7YES</recordid><startdate>20040201</startdate><enddate>20040201</enddate><creator>Cessna, J.T</creator><creator>Zimmerman, B.E</creator><creator>Unterweger, M.P</creator><creator>Golas, D.B</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040201</creationdate><title>Establishment of transfer standard for holmium-166-DOTMP</title><author>Cessna, J.T ; Zimmerman, B.E ; Unterweger, M.P ; Golas, D.B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c364t-ea24c7d45680735d8f1e924ac6bea6c4cba5ba1aeaa945f45f37ab0cb2c2def13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Calibration - standards</topic><topic>Holmium-166</topic><topic>Nuclear medicine</topic><topic>Organometallic Compounds - analysis</topic><topic>Organometallic Compounds - standards</topic><topic>Organophosphorus Compounds - analysis</topic><topic>Organophosphorus Compounds - standards</topic><topic>Quality Control</topic><topic>Radiometry - instrumentation</topic><topic>Radiometry - methods</topic><topic>Radiometry - standards</topic><topic>Radionuclide calibrator</topic><topic>Radiopharmaceuticals - analysis</topic><topic>Radiopharmaceuticals - standards</topic><topic>Reference Standards</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Specimen Handling - methods</topic><topic>Specimen Handling - standards</topic><topic>Transfer standard</topic><topic>United States</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cessna, J.T</creatorcontrib><creatorcontrib>Zimmerman, B.E</creatorcontrib><creatorcontrib>Unterweger, M.P</creatorcontrib><creatorcontrib>Golas, D.B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Applied radiation and isotopes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cessna, J.T</au><au>Zimmerman, B.E</au><au>Unterweger, M.P</au><au>Golas, D.B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Establishment of transfer standard for holmium-166-DOTMP</atitle><jtitle>Applied radiation and isotopes</jtitle><addtitle>Appl Radiat Isot</addtitle><date>2004-02-01</date><risdate>2004</risdate><volume>60</volume><issue>2</issue><spage>505</spage><epage>510</epage><pages>505-510</pages><issn>0969-8043</issn><eissn>1872-9800</eissn><abstract>The measurement of
166Ho, both as a chloride solution and as [
166Ho]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylenephoonic acid (DOTMP), was examined for four models of radionuclide calibrators: Capintec CRC-35R (two chambers), Capintec 712MX, AtomLab 100 (two chambers), and a Capintec CRC-12. Holmium-166 chloride was measured as 16
ml in 20-ml glass dose vials. Diagnostic imaging level [
166Ho]DOTMP solutions, nominally 400
MBq
g
−1, were measured as 12
ml in 20-ml dose vials. Finally, therapeutic level [
166Ho]DOTMP solutions, nominally 9
GBq
g
−1, were measured as aliquots of 100–500
μl in sealed plastic vials of 10-ml saline. Single calibration factors for each instrument manufacturer are recommended for 12–16-ml of either solution in 20-ml glass dose vials, (673±9)×10 and 72.7±0.7, for the Capintec and AtomLab models, respectively. Calibration factors recommended for the therapeutic dose geometry are (706±6)×10 and 68.7±1.3, for the Capintec and AtomLab models, respectively. The calibration factors recommended for an NIST 5-ml ampoule are (686±5)×10 and 70.9±0.4 for the Capintec and AtomLab models, respectively.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>14987693</pmid><doi>10.1016/j.apradiso.2003.11.067</doi><tpages>6</tpages></addata></record> |
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| subjects | Calibration - standards Holmium-166 Nuclear medicine Organometallic Compounds - analysis Organometallic Compounds - standards Organophosphorus Compounds - analysis Organophosphorus Compounds - standards Quality Control Radiometry - instrumentation Radiometry - methods Radiometry - standards Radionuclide calibrator Radiopharmaceuticals - analysis Radiopharmaceuticals - standards Reference Standards Reproducibility of Results Sensitivity and Specificity Specimen Handling - methods Specimen Handling - standards Transfer standard United States |
| title | Establishment of transfer standard for holmium-166-DOTMP |
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