Time Course of NADH Oxidase, Inducible Nitric Oxide Synthase and Peroxynitrite in Diabetic Retinopathy in the BBZ/WOR Rat

This study investigated the time course of NADH oxidase, a source of superoxide in the vascular endothelium, inducible nitric oxide synthase (iNOS), and peroxynitrite (ONOO−) in the BBZ/Wor rat, a spontaneous model of noninsulin dependent diabetes (NIDDM). Colloidal gold-labeled immunocytochemical s...

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Veröffentlicht in:	Nitric oxide 2002-05, Vol.6 (3), p.295-304
Hauptverfasser:	Ellis, E.Ann, Guberski, Dennis L., Hutson, Brenda, Grant, Maria B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals diabetes Diabetic Retinopathy - metabolism Immunohistochemistry inducible nitric oxide synthase Kinetics Male Multienzyme Complexes - metabolism NADH, NADPH Oxidoreductases - metabolism Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II nitrotyrosine oxidative stress peroxynitrite Peroxynitrous Acid - metabolism Rats retinopathy
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