Identification of differentially expressed genes induced by transient ischemic stroke

We have used a rat model of focal cerebral ischemia to investigate changes in gene expression that occur during stroke. To monitor these changes, we employed representational difference analysis–polymerase chain reaction (PCR). A total of 128 unique gene fragments were isolated, and we selected 13 o...

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Veröffentlicht in:	Brain research. Molecular brain research. 2002-05, Vol.101 (1), p.12-22
Hauptverfasser:	Schwarz, David A, Barry, Guy, Mackay, Kenneth B, Manu, Frank, Naeve, Gregory S, Vana, Alicia M, Verge, Gail, Conlon, Paul J, Foster, Alan C, Maki, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences BIS protein Brain Ischemia - genetics Brain Ischemia - metabolism Brain Ischemia - physiopathology Cerebral Cortex - metabolism Cerebral Cortex - pathology Cerebral Cortex - physiopathology Cerebral Infarction - genetics Cerebral Infarction - metabolism Cerebral Infarction - physiopathology Cyr61 protein DNA, Complementary - analysis Endothelium, Vascular - metabolism Gene Expression Regulation - physiology LOX-1 LOX-1 gene Male Medical sciences Middle cerebral artery occlusion Narp protein Neostriatum - metabolism Neostriatum - pathology Neostriatum - physiopathology Neuroglia - metabolism Neurology Rats Rats, Sprague-Dawley Receptors, LDL - genetics Receptors, Oxidized LDL Reperfusion Injury - genetics Reperfusion Injury - metabolism Reperfusion Injury - physiopathology RNA, Messenger - metabolism Scavenger Receptors, Class E Stroke Stroke - genetics Stroke - metabolism Stroke - physiopathology Subtraction Up-Regulation - physiology Vascular diseases and vascular malformations of the nervous system
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