Evaluation of Th1, Th2 and immunosuppressive cytokine mRNA expression within the colonic mucosa of dogs with idiopathic lymphocytic–plasmacytic colitis

The objective of this study was to evaluate the expression of the immunoregulatory and pro-inflammatory cytokines interleukin (IL)-2, IL-4, IL-6, IL-12p35, IL-12p40, interferon-gamma (IFN-γ), and tumour necrosis factor-alpha (TNF-α), and the expression of the predominantly immunosuppressive cytokine...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2002-07, Vol.86 (3), p.205-214
Hauptverfasser:	Ridyard, Alison E., Nuttall, Timothy J., Else, Rod W., Simpson, James W., Miller, Hugh R.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Southern - veterinary Colitis - immunology Colitis - veterinary Cytokines Cytokines - analysis Cytokines - biosynthesis Cytokines - genetics DNA, Complementary - chemistry Dog Dog Diseases - immunology Dogs Female Gene Expression Regulation - immunology Inflammatory bowel disease Interleukin-2 Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Lymphocytic–plasmacytic colitis Male Reverse Transcriptase Polymerase Chain Reaction - veterinary RNA, Messenger - biosynthesis RNA, Messenger - genetics T-helper 1 Th1 Cells - immunology Th2 Cells - immunology Tumour necrosis factor-alpha
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