Aberrant D1 and D3 Dopamine Receptor Transregulation in Hypertension

ABSTRACT—Dopamine plays a role in the regulation of blood pressure by inhibition of sodium transport in renal proximal tubules (RPTs) and relaxation of vascular smooth muscles. Because dopamine receptors can regulate and interact with each other, we studied the interaction of D1 and D3 receptors in...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2004-03, Vol.43 (3), p.654-660
Hauptverfasser:	Zeng, Chunyu, Wang, Dan, Asico, Laureano D, Welch, William J, Wilcox, Christopher S, Hopfer, Ulrich, Eisner, Gilbert M, Felder, Robin A, Jose, Pedro A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cell Line Clinical manifestations. Epidemiology. Investigative techniques. Etiology Coronary Vessels - cytology Dopamine Agonists - pharmacology Fenoldopam - pharmacology Fundamental and applied biological sciences. Psychology Hemodynamics. Rheology Humans Hypertension - metabolism Hypertension - physiopathology Kidney Tubules, Proximal - drug effects Kidney Tubules, Proximal - metabolism Male Medical sciences Mesenteric Arteries - physiopathology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Precipitin Tests Rats Rats, Inbred SHR Rats, Inbred WKY Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - agonists Receptors, Dopamine D2 - metabolism Receptors, Dopamine D3 Vasodilation Vertebrates: cardiovascular system
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