Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

Ski-interacting protein (SKIP), a vitamin D receptor (VDR) coactivator, also functions as a repressor in Notch signalling in association with the corepressor SMRT. Here we show that SKIP bifunctionally modulates (activates or represses) Retinoid-X receptor (RXR)- and VDR-dependent gene transcription...

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Veröffentlicht in:	Biochemical and biophysical research communications 2004-03, Vol.315 (4), p.1070-1076
Hauptverfasser:	Leong, Gary M, Subramaniam, Nanthakumar, Issa, Laura L, Barry, Janelle B, Kino, Tomoshige, Driggers, Paul H, Hayman, Michael J, Eisman, John A, Gardiner, Edith M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyltransferases - metabolism Animals Cell Cycle Proteins - metabolism Cell Line Cercopithecus aethiops COS Cells DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene Expression Histone Acetyltransferases Mice N-CoR/SMRT NcoA-62 NIH 3T3 Cells Nuclear Proteins - genetics Nuclear Proteins - metabolism Nuclear receptor Nuclear Receptor Co-Repressor 2 p300 p300-CBP Transcription Factors Receptors, Calcitriol - genetics Receptors, Calcitriol - metabolism Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Retinoic Acid - genetics Receptors, Retinoic Acid - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Repressor Proteins - genetics Repressor Proteins - metabolism Retinoid X receptor Retinoid X Receptors Sequence Deletion SKIP Transcription Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Transcriptional Activation Vitamin D
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