Serotonergic/glutamatergic interactions: the effects of mGlu2/3 receptor ligands in rats trained with LSD and PCP as discriminative stimuli

On the basis of electrophysiological evidence, it has been proposed that both antagonism of NMDA receptors by drugs such as PCP and stimulation of 5- HT(2A) receptors by drugs such as LSD result in the release of glutamate. Furthermore, it has been observed that antagonists and agonists at mGlu(2/3)...

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Veröffentlicht in:	Psychopharmacologia 2004-03, Vol.172 (2), p.233-240
Hauptverfasser:	WINTER, J. C, ECKLER, J. R, RABIN, R. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Discrimination (Psychology) - drug effects Discrimination (Psychology) - physiology Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Ligands Lysergic Acid Diethylamide - pharmacology Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Phencyclidine - pharmacology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred F344 Receptors, Metabotropic Glutamate - agonists Receptors, Metabotropic Glutamate - physiology Receptors, Serotonin - physiology Serotonin Antagonists - pharmacology Serotonin Receptor Agonists - pharmacology
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