The Androgen Receptor Can Promote β-Catenin Nuclear Translocation Independently of Adenomatous Polyposis Coli

We provide evidence that the androgen receptor (AR) can promote nuclear translocation of β-catenin in LNCaP and PC3 prostate cancer cells. Using AR-expressing cells (LNCaP) and non-AR-expressing cells (PC3) we showed by time course cell fractionation that the AR can shuttle β-catenin into the nucleu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2002-05, Vol.277 (20), p.17933-17943
Hauptverfasser:	Mulholland, David J., Cheng, Helen, Reid, Kim, Rennie, Paul S., Nelson, Colleen C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus adenomatous polyposis coli Adenomatous Polyposis Coli - metabolism Androgen-Binding Protein - genetics Androgen-Binding Protein - metabolism Animals b-catenin beta Catenin Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell Nucleus - metabolism Cytoskeletal Proteins - metabolism DNA - metabolism Glycogen Synthase Kinase 3 Glycogen Synthase Kinases Humans Male Metribolone - metabolism probasin Promoter Regions, Genetic Prostatic Neoplasms - metabolism Receptors, Androgen - metabolism Trans-Activators Transcription, Genetic Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!