Plasma Membrane Phospholipid Scramblase 1 Is Enriched in Lipid Rafts and Interacts with the Epidermal Growth Factor Receptor

We have identified physical and functional interactions between the epidermal growth factor (EGF) receptor and phospholipid scramblase 1 (PLSCR1), an endofacial plasma membrane protein proposed to affect phospholipid organization. PLSCR1, a palmitoylated protein, was found to partition with the EGF...

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Veröffentlicht in:	Biochemistry (Easton) 2002-05, Vol.41 (20), p.6338-6345
Hauptverfasser:	Sun, Jun, Nanjundan, Meera, Pike, Linda J, Wiedmer, Therese, Sims, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	Carrier Proteins - biosynthesis Carrier Proteins - metabolism Carrier Proteins - physiology Endocytosis - physiology Epidermal Growth Factor - pharmacology ErbB Receptors - metabolism Humans KB Cells Membrane Microdomains - enzymology Membrane Microdomains - metabolism Membrane Proteins - biosynthesis Membrane Proteins - metabolism Membrane Proteins - physiology Phospholipid Transfer Proteins Phospholipids - metabolism Phosphorylation Phosphotyrosine - metabolism Proto-Oncogene Proteins c-abl - physiology
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