Pityriarubins, Biologically Active Bis(indolyl)spirans from Cultures of the Lipophilic Yeast Malassezia furfur

Indole alkaloids, such as pityriarubin A (1), may be of importance for the pathogenesis of the common skin disease pityriasis versicolor. The metabolite 1 is produced in cultures of the lipophilic yeast Malassezia furfur with tryptophan present as the sole source of nitrogen. The structures of the p...

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