Immediate Repair Compared with Surveillance of Small Abdominal Aortic Aneurysms

Whether clinically stable small abdominal aortic aneurysms should be surgically repaired or monitored with periodic noninvasive imaging is controversial. This study compared the two approaches in patients with aneurysms 4.0 to 5.4 cm in diameter. After a mean follow-up of nearly five years, there wa...

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Veröffentlicht in:The New England journal of medicine 2002-05, Vol.346 (19), p.1437-1444
Hauptverfasser: Lederle, Frank A, Wilson, Samuel E, Johnson, Gary R, Reinke, Donovan B, Littooy, Fred N, Acher, Charles W, Ballard, David J, Messina, Louis M, Gordon, Ian L, Chute, Edmund P, Krupski, William C, Busuttil, Steven J, Barone, Gary W, Sparks, Steven, Graham, Linda M, Rapp, Joseph H, Makaroun, Michel S, Moneta, Gregory L, Cambria, Robert A, Makhoul, Raymond G, Eton, Darwin, Ansel, Howard J, Freischlag, Julie A, Bandyk, Dennis
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Sprache:eng
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Zusammenfassung:Whether clinically stable small abdominal aortic aneurysms should be surgically repaired or monitored with periodic noninvasive imaging is controversial. This study compared the two approaches in patients with aneurysms 4.0 to 5.4 cm in diameter. After a mean follow-up of nearly five years, there was no survival advantage associated with immediate surgical repair. This study compared the two approaches in patients with aneurysms of 4.0 to 5.4 cm. There was no survival advantage with immediate surgical repair. Each year in the United States, 9000 deaths result from rupture of abdominal aortic aneurysms. 1 Another 33,000 patients undergo elective repair of asymptomatic abdominal aortic aneurysms to prevent rupture, which results in 1400 to 2800 operative deaths. 2 , 3 Because most abdominal aortic aneurysms never rupture, 4 elective repair is undertaken only when the risk of rupture is considered high. The strongest known predictor of rupture is the maximal diameter of the aneurysm. 5 , 6 Elective repair has been recommended for patients with aneurysms of 4.0 cm or more in diameter who do not have medical contraindications, 7 although others have advocated the use . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa012573