Distinct roles for protease-activated receptors 1 and 2 in vasomotor modulation in rat superior mesenteric artery

Protease-activated receptors (PARs) 1 and 2 are expressed in various blood vessels including rat aorta, modulating vascular tone. We investigated the roles of PAR-1 and PAR-2 in vasomotor modulation in rat superior mesenteric artery. Effects of the PAR-2-activating peptide Ser-Leu-Ile-Gly-Arg-Leu-am...

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Veröffentlicht in:	Cardiovascular research 2004-03, Vol.61 (4), p.683-692
Hauptverfasser:	KAWABATA, Atsufumi, KUBO, Satoko, NAKAYA, Yumiko, ISHIKI, Tsuyoshi, KURODA, Ryotaro, SEKIGUCHI, Fumiko, KAWAO, Naoyuki, NISHIKAWA, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Aorta - drug effects Biological and medical sciences Cardiology. Vascular system In Vitro Techniques Indomethacin - pharmacology Male Medical sciences Mesenteric Artery, Superior - drug effects NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Oligopeptides - pharmacology Rats Rats, Wistar Receptor, PAR-1 - physiology Receptor, PAR-2 - physiology Trypsin - pharmacology Vasodilation - drug effects
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