Heat shock protein 70 fused to or complexed with Hantavirus nucleocapsid protein significantly enhances specific humoral and cellular immune responses in C57BL/6 mice

Summary Heat shock proteins (HSPs) are known to act as an effective molecular adjuvant to enhance the induction of antigen peptide-specific cellular immunity, when coupled with the antigen or peptide. Hantaan virus (HTNV) nucleocapsid protein (NP) is relatively conserved among hantaviruses and highl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2008-06, Vol.26 (25), p.3175-3187
Hauptverfasser:	Li, Jing, Li, Kai Nan, Gao, Juan, Cui, Ji Hong, Liu, Yan Fang, Yang, Shou Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Antibodies, Viral - blood Antibody Formation - drug effects Antibody Formation - immunology Antigens Applied microbiology Biological and medical sciences Capsid Proteins - administration & dosage Capsid Proteins - chemistry Capsid Proteins - immunology Cytotoxic T lymphocyte Cytotoxicity Deoxyribonucleic acid DNA Enzyme-Linked Immunosorbent Assay Flow Cytometry Fundamental and applied biological sciences. Psychology Hantaan virus Hantavirus Hantavirus - chemistry Heat-shock protein 70 HSP70 Heat-Shock Proteins - administration & dosage HSP70 Heat-Shock Proteins - chemistry HSP70 Heat-Shock Proteins - immunology Humoral immunity Immune response Immune system Immunity, Cellular - drug effects Immunity, Cellular - immunology Immunization Infections Lymphocytes Mice Mice, Inbred C57BL Microbiology Miscellaneous Mortality Nucleocapsid protein Peptides Protein vaccine Proteins Recombinant Fusion Proteins - immunology RNA polymerase Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral Core Proteins - administration & dosage Viral Core Proteins - chemistry Viral Core Proteins - immunology Viral Vaccines - administration & dosage Viral Vaccines - immunology Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!