Chemometric and chemoinformatic analyses of anabolic and androgenic activities of testosterone and dihydrotestosterone analogues

Predictive quantitative structure–activity relationship (QSAR) models of anabolic and androgenic activities for the testosterone and dihydrotestosterone steroid analogues were obtained by means of multiple linear regression using quantum and physicochemical molecular descriptors (MD) as well as a ge...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry 2008-06, Vol.16 (12), p.6448-6459
Hauptverfasser:	Alvarez-Ginarte, Yoanna María, Crespo-Otero, Rachel, Marrero-Ponce, Yovani, Noheda-Marin, Pedro, Garcia de la Vega, Jose Manuel, Montero-Cabrera, Luis Alberto, Ruiz García, José Alberto, Caldera-Luzardo, José A., Alvarado, Ysaias J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Anabolic Agents - chemistry Anabolic Agents - pharmacology Anabolic and androgenic activities Androgens - chemistry Androgens - genetics Androgens - pharmacology Biological and medical sciences Cluster Analysis Computer Simulation Dihydrotestosterone - analogs & derivatives Genetic algorithm Hormones. Endocrine system Humans Male Medical sciences Models, Chemical Pharmacology. Drug treatments QSAR model Quantitative Structure-Activity Relationship Quantum and physicochemical molecular descriptor Testosterone - analogs & derivatives Testosterone - genetics Testosterone and dihydrotestosterone steroid analogues
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!