HBOC-201 as an Alternative to Blood Transfusion : Efficacy and Safety Evaluation in a Multicenter Phase III Trial in Elective Orthopedic Surgery

The ability of hemoglobin based oxygen carrier-201 (HBOC-201) to safely reduce and/or eliminate perioperative transfusion was studied in orthopedic surgery patients. A randomized, single-blind, packed red blood cell (PRBC)-controlled, parallel-group multicenter study was conducted. Six hundred eight...

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Veröffentlicht in:	The Journal of trauma, injury, infection, and critical care injury, infection, and critical care, 2008-06, Vol.64 (6), p.1484-1497
Hauptverfasser:	JAHR, Jonathan S, MACKENZIE, Colin, PEARCE, L. Bruce, PITMAN, Arkadiy, GREENBURG, A. Gerson
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Loss, Surgical - prevention & control Blood Substitutes - administration & dosage Diseases of the osteoarticular system Elective Surgical Procedures Erythrocyte Transfusion Evaluation Studies as Topic Female Follow-Up Studies General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation Hemoglobins - administration & dosage Humans Male Medical sciences Middle Aged Orthopedic Procedures - methods Orthopedic surgery Probability Risk Assessment Safety Single-Blind Method Statistics, Nonparametric Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Treatment Outcome
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