Soluble proteins and haptens on bone marrow-derived dendritic cells are presented to host CD4 T cells in an MHC-restricted manner

Because of their potent antigen-presenting capacity, dendritic cells (DC) have been used extensively in immunotherapy protocols. Our purpose was to functionally characterize mouse bone marrow-derived DC (BMDC) in vitro (in protein antigen- and hapten-specific assays) and in vivo (injecting soluble p...

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Veröffentlicht in:	International immunology 2002-05, Vol.14 (5), p.493-502
Hauptverfasser:	Olasz, Edit B, Linton, Jay, Katz, Stephen I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Bone Marrow Cells - cytology Cytochrome c Group - immunology Dendritic Cells - immunology Egg Proteins - immunology Female Haptens - chemistry Haptens - immunology Histocompatibility Antigens - physiology Hybridomas - metabolism Hypersensitivity, Delayed - immunology Interleukin-4 - metabolism Langerhans Cells - immunology Membrane Glycoproteins - metabolism Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred Strains Picryl Chloride - immunology Proteins - metabolism Solubility T-Lymphocyte Subsets - immunology T-Lymphocytes, Helper-Inducer - immunology
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