Adipokine Protein Expression Pattern in Growth Hormone Deficiency Predisposes to the Increased Fat Cell Size and the Whole Body Metabolic Derangements

Context: GH deficiency (GHD) in adults is associated with central adiposity, dyslipidemia, and insulin resistance. Objective: The objective of the study was to test the hypothesis that GHD might change the spectrum of adipokines and thus influence the adipose tissue and the whole-body metabolic and...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2008-06, Vol.93 (6), p.2255-2262
Hauptverfasser:	Ukropec, Jozef, Penesová, Adela, Škopková, Martina, Pura, Mikuláš, Vlček, Miroslav, Rádiková, Žofia, Imrich, Richard, Ukropcová, Barbara, Tajtáková, Mária, Koška, Juraj, Zórad, Štefan, Belan, Vítazoslav, Vaňuga, Peter, Payer, Juraj, Eckel, Juergen, Klimeš, Iwar, Gašperíková, Daniela
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes, White - metabolism Adipocytes, White - pathology Adipogenesis Adipokines - metabolism Adult Biological and medical sciences Case-Control Studies Cell Enlargement Cell Proliferation Cross-Sectional Studies Disease Susceptibility - metabolism Dwarfism, Pituitary - metabolism Dwarfism, Pituitary - pathology Endocrinopathies Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Humans Inflammation - metabolism Male Medical sciences Metabolic Diseases - etiology Metabolic Diseases - metabolism Metabolic Diseases - pathology Obesity - metabolism Protein Array Analysis Thinness - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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