Structure of the integrin alphaIIb transmembrane segment

Integrin cell-adhesion receptors transduce signals bidirectionally across the plasma membrane via the single-pass transmembrane segments of each alpha and beta subunit. While the beta3 transmembrane segment consists of a linear 29-residue alpha-helix, the structure of the alphaIIb transmembrane segm...

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Veröffentlicht in:	The Journal of biological chemistry 2008-06, Vol.283 (23), p.16162-16168
Hauptverfasser:	Lau, Tong-Lay, Dua, Varun, Ulmer, Tobias S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs - physiology Amino Acid Sequence Cell Membrane - chemistry Cell Membrane - metabolism Humans Molecular Sequence Data Platelet Glycoprotein GPIIb-IIIa Complex - chemistry Platelet Glycoprotein GPIIb-IIIa Complex - metabolism Platelet Membrane Glycoprotein IIb - chemistry Platelet Membrane Glycoprotein IIb - metabolism Protein Structure, Tertiary - physiology Protein Subunits - chemistry Protein Subunits - metabolism Sequence Alignment Signal Transduction - physiology
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