A Central Institutional Review Board for Multi-Institutional Trials
These are difficult times for the nation's system of protection for human subjects in research. 1 – 10 On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to “rev...
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| Veröffentlicht in: | The New England journal of medicine 2002-05, Vol.346 (18), p.1405-1408 |
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| container_issue | 18 |
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| container_title | The New England journal of medicine |
| container_volume | 346 |
| creator | Killen, Jack Christian, Michaele C Abrams, Jeffrey S McCabe, Mary S Goldberg, Jacquelyn L Mauer, Joan K Wittes, Robert E |
| description | These are difficult times for the nation's system of protection for human subjects in research.
1
–
10
On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to “review too much, too quickly, with too little expertise,” and with inadequate resources.
6
One consequence is that there is minimal, often perfunctory, review of ongoing research. In addition, IRB members have become disillusioned as a result of both public criticism concerning the perceived failures of the boards and the increasing amount of . . . |
| doi_str_mv | 10.1056/NEJM200205023461814 |
| format | Article |
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1
–
10
On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to “review too much, too quickly, with too little expertise,” and with inadequate resources.
6
One consequence is that there is minimal, often perfunctory, review of ongoing research. In addition, IRB members have become disillusioned as a result of both public criticism concerning the perceived failures of the boards and the increasing amount of . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM200205023461814</identifier><identifier>PMID: 11986418</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Bioethics ; Biological and medical sciences ; Clinical trials ; Clinical Trials as Topic ; Ethics ; Ethics Committees, Research - organization & administration ; Humans ; Medical research ; Medical sciences ; Multicenter Studies as Topic ; National Institutes of Health (U.S.) ; Pilot Projects ; Review boards ; United States</subject><ispartof>The New England journal of medicine, 2002-05, Vol.346 (18), p.1405-1408</ispartof><rights>Copyright © 2002 Massachusetts Medical Society. All rights reserved.</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-fb12e0ce4629201a6026b6a6b1ce6a677128490e0672be2f21eeefd4ec4732793</citedby><cites>FETCH-LOGICAL-c414t-fb12e0ce4629201a6026b6a6b1ce6a677128490e0672be2f21eeefd4ec4732793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM200205023461814$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM200205023461814$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2745,2746,26082,27903,27904,52360,54042</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13639513$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11986418$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Killen, Jack</creatorcontrib><creatorcontrib>Christian, Michaele C</creatorcontrib><creatorcontrib>Abrams, Jeffrey S</creatorcontrib><creatorcontrib>McCabe, Mary S</creatorcontrib><creatorcontrib>Goldberg, Jacquelyn L</creatorcontrib><creatorcontrib>Mauer, Joan K</creatorcontrib><creatorcontrib>Wittes, Robert E</creatorcontrib><title>A Central Institutional Review Board for Multi-Institutional Trials</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>These are difficult times for the nation's system of protection for human subjects in research.
1
–
10
On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to “review too much, too quickly, with too little expertise,” and with inadequate resources.
6
One consequence is that there is minimal, often perfunctory, review of ongoing research. 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1
–
10
On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to “review too much, too quickly, with too little expertise,” and with inadequate resources.
6
One consequence is that there is minimal, often perfunctory, review of ongoing research. In addition, IRB members have become disillusioned as a result of both public criticism concerning the perceived failures of the boards and the increasing amount of . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>11986418</pmid><doi>10.1056/NEJM200205023461814</doi><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2002-05, Vol.346 (18), p.1405-1408 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Bioethics Biological and medical sciences Clinical trials Clinical Trials as Topic Ethics Ethics Committees, Research - organization & administration Humans Medical research Medical sciences Multicenter Studies as Topic National Institutes of Health (U.S.) Pilot Projects Review boards United States |
| title | A Central Institutional Review Board for Multi-Institutional Trials |
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