A novel approach to sustained pseudoephedrine release: Differentially coated mini-tablets in HPMC capsules

We developed and optimized a novel pseudoephedrine hydrochloride (PSE) sustained-release dosage form. The system comprises immediate-release mini-tablets (IRMT) and sustained-release mini-tablets (SRMT) contained in a hydroxypropyl methylcellulose (HPMC) capsule. The IRMT contained PSE, excipients a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of pharmaceutics 2008-07, Vol.359 (1), p.46-52
Hauptverfasser:	Ishida, Makoto, Abe, Kenichi, Hashizume, Minoru, Kawamura, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Capsules Cellulose - analogs & derivatives Cellulose - chemistry Chemistry, Pharmaceutical Delayed-Action Preparations Ethylcellulose Excipients - chemistry General pharmacology Hydroxypropyl methylcellulose Hypromellose Derivatives Immediate release Medical sciences Methylcellulose - analogs & derivatives Methylcellulose - chemistry Mini-tablets Nasal Decongestants - chemistry Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Pseudoephedrine - chemistry Pseudoephedrine hydrochloride Solubility Sustained release Tablets Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!